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我可以在哺乳期服用可待因吗? 这对哺乳母亲和孩子是否安全? |
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化合物的咳嗽、疼痛的药物治疗。 细胞色素P450-CYP2D6酶催化吗啡。 它是排泄母乳中在少量的，大大低于所使用的剂量为新生儿和婴儿。 等离子体层次的婴儿其母亲把他们都很低，低于通常的治疗水平和假设的一个相对剂量微不足道的，不到1.5%(每个迷宫1993年，瑙姆堡1988年，芬德利1981年)，所以它被认为是安全使用母乳喂养期间(Bar-盎司2003年，谁2002年，AAP2001年，莫雷蒂2000年，Spigset2000年，米切尔1999年，每个迷宫1993年)。 然而，过度镇静的母亲或婴儿可能发生如果他们是快速的代谢者可待因吗啡，由于过量的基因链接到P450-2D6酶：这发生在 |
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您是否想问其他问题 可待因 ? |
科学文献
这些科学出版物证实了用于母乳喂养的药物的风险水平：- https://www.fda.gov/downloads/Drugs/DrugSafety/UCM553814.pdf
- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/27050859
- http://www.scielo.br/pdf/anp/v74n3/0004-282X-anp-74-03-0262.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/27540198
- http://www.royalberkshire.nhs.uk/patient-information-leaflets/Maternity/Maternity---codeine-and-breastfeeding.htm
- http://www.ncbi.nlm.nih.gov/pubmed/25578245
- http://www.ncbi.nlm.nih.gov/pubmed/25836677
- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/21-drug-dependency-protocol-english.pdf
- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/21-drug-dependency-protocol-spanish.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/25809057
- http://www.ncbi.nlm.nih.gov/pubmed/25927109
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369625/pdf/0610241.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/24796391
- http://onlinelibrary.wiley.com/doi/10.1111/anae.12716/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/23968886
- http://www.ncbi.nlm.nih.gov/pubmed/23922910
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726489/pdf/pone.0070073.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23979084
- http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23178070
- https://www.sps.nhs.uk/articles/codeine-and-breastfeeding-is-it-safe-and-what-are-the-alternatives/
- http://www.ncbi.nlm.nih.gov/pubmed/21996159
- http://www.ncbi.nlm.nih.gov/pubmed/22148986
- http://www.tandfonline.com/doi/pdf/10.3109/15563650.2011.635147?needAccess=true
- http://www.ncbi.nlm.nih.gov/pubmed/21241245
- http://www.ncbi.nlm.nih.gov/pubmed/21894275
- http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/19628064
- http://www.ncbi.nlm.nih.gov/pubmed/18719619
- http://www.ncbi.nlm.nih.gov/pubmed/19710640
- http://www.ncbi.nlm.nih.gov/pubmed/19910591
- http://www.ncbi.nlm.nih.gov/pubmed/18998750
- http://www.ncbi.nlm.nih.gov/pubmed/18722850
- http://www.ncbi.nlm.nih.gov/pubmed/18722857
- http://www.ncbi.nlm.nih.gov/pubmed/18781855
- http://www.ncbi.nlm.nih.gov/pubmed/17872605
- http://www.ncbi.nlm.nih.gov/pubmed/17872775
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949207/pdf/0531005.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16920476
- http://www.ncbi.nlm.nih.gov/pubmed/15051581
- http://www.ncbi.nlm.nih.gov/pubmed/14583068
- http://whqlibdoc.who.int/hq/2002/55732.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11533352
- http://pediatrics.aappublications.org/content/108/3/776.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10937472
- http://www.ncbi.nlm.nih.gov/pubmed/11013791
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2145042/pdf/canfamphys00031-0055.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10776186
- http://www.ncbi.nlm.nih.gov/pubmed/8498418
- http://www.ncbi.nlm.nih.gov/pubmed/8260056
- http://www.ncbi.nlm.nih.gov/pubmed/3341293
- http://www.ncbi.nlm.nih.gov/pubmed/7214793
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