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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Pentosan Polysulfate Sodium during lactation?
Is it safe for a nursing mother and a child?

Sulfated polysaccharide of plant origin with anticoagulant and fibrinolytic properties similar to heparin. Topical, oral and parenteral administration (subcutaneous, intramuscular or intravenous).Orally used for pain relief of the urinary tract on interstitial cystitis.Topically used on superficial venous disorders, hemorrhoids and hematomas. At latest update relevant published data on its excretion into breast milk were not found. Because of a high molecular weight, excretion into breastmilk in significant amounts seems very unlikely.A low or not at all oral bioavailability (Faaij 1999, Simon 2005) makes it seems difficult the pass into the infant’s plasma through the breast milk ingested, except for premature infants and immediate neonatal period, in which there may be an increased intestinal permeability. Do not apply it on the chest to prevent the infant from ingesting it; if necessary, do it after a feeding and clean it up thoroughly with water before the next one.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Trade Names

The main trade names in different countries containing in its composition Pentosan Polysulfate Sodium:

Comments  

+3 #2 Reviewer: Seshet, 45-54 Female on Treatment for 6 months to less than 1 year 2018-07-31 12:23
I took Elmiron several years ago for Interstitial Cystisis. I took it for six month and had no improvement at all!!
+3 #1 Reviewer: Eartha, 45-54 Female on Treatment for 1 to 6 months (Patient) 2017-12-13 04:13
Trying to remember to take this 3 times a day is hard. And to add to that, dosing is 1 hour before a meal or 2 hours after. I am not convinced this medication is even working. I have been on it for 3 months and feel no better than the day it was prescribed. Even the medication info says it can take 3 months to a year to see results. I am discouraged about the effectiveness of this drug.

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