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pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Otilonium Bromide during lactation?
Is it safe for a nursing mother and a child?

Anticholinergic drug used as spasmolytic for functional gastrointestinal disorders. At latest update relevant published data on excretion into breast milk were not found. It acts locally on the intestinal mucosa. Absorption through the intestine is practically absent (Evangelista 2004, Catalogo 2008), with an excretion being almost 100% unmodified in feces that is determinant for the extremely low levels reached in the plasma (Zhao 2010: <0.02 mg / L), which causes the passage through breastmilk in significant amounts must be very unlikely.Side effects are mild and very rarely seen. Although anticholinergics may reduce milk production, however, because of its poor absorption it would not be the case with Otilonium.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/20810330
  2. http://www.ncbi.nlm.nih.gov/pubmed/18200532
  3. http://www.ncbi.nlm.nih.gov/pubmed/15579053

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