Antispasmodic drug used for treatment of Irritable Colon Syndrome. At latest update, no relevant published data concerning excretion into breast milk were found. Pharmacokinetic data support the likelihood of significant excretion into breast milk, despite of the excretion in the milk of animals has shown to be poor (less than 0.1%). Side effects of Trimebutine are rare and generally mild. This medication is not authorized for children under 12 years old. However, it has been used in neonates and infants in some countries. Anticholinergic drugs may reduce milk production. Use the minimal necessary dose as possible and avoid long-term use whenever a decrease in milk production would appear. Do not use it soon after birth or in case of premature infant.