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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Nedocromil Sodium during lactation?
Is it safe for a nursing mother and a child?

It is administered by inhalation for prevention of asthma and atopic rhinitis and as eye drops for allergic conjunctivitis. At latest update relevant published data on excretion into breast milk were not found. Pharmacokinetic data (very low bioavailability after inhalation, orally or ophthalmic application with very low plasma levels achieved, moderately elevated molecular weight and a high protein-binding capacity) would render it rather unlikely a significant passage into breastmilk, which would also cause a poor absorption through the infant’s gut . It is a well tolerated drug with indeed no side effects and none of them reportedly to be serious. The small dose used and low plasma absorption of most inhaled preparations (either buccal or nasal), topically apply as ophthalmologic or dermatologic preparations, make it unlikely any passage in a significant amount into breastmilk.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/2825746

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