Intravenous administration, every 6 to 8 hours. Like other beta-lactams, it is excreted in breast milk in a clinically insignificant amount (Matsuda 1988, Ito 1988). Its practically no oral bioavailability would make it difficult for the infant to pass through the breast milk ingested, except in preterm infants and an immediate neonatal period in which there may be increased intestinal permeability. Mediation of authorized use in infants and neonates (Merck 2016). The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981).