Polypeptide with anti-microbial activity that is produced by strains of Bacillus licheniformis or Bacillus subtilis. Indicated for topical use (high nephrotoxicity with systemic use) Not absorbed through skin, mucosa or intestinal tract. When orally taken it is destroyed by the gut with no pass into the blood stream. Preferably, avoid it on the breast or clear it out before nursing. Avoid use of creams, gels and other topical medication containing paraffin (petroleum-derived mineral oil) in order to avoid the risk of absorption by the child. The WHO Model List of Essential Medicines 2002 rates it as compatible with breastfeeding.