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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Prednisolone during lactation?
Is it safe for a nursing mother and a child?

Excreted into breast milk in non-significant amount with no problems reported in breastfed infants whose mothers were treated at a daily dose as high as 7.5 mg for a long time period. At a daily dose of 60 mg used for treatment of Herpes or Gestational Pemphigus no harm effects on breastfed infants have been reported. On long term treatments it would be advisable to wait for 3 - 4 hours until the next nurse to minimize the transfer of drug to breast milk. At high doses, intra-articular treatment with other steroid drugs (Triamcinolone) have transiently affected milk production. Steroids administered before delivery may delay initiation of phase II of Lactogenesis ("milk come in") and decrease milk production in the first postpartum week. Decreased production has been seen while taking Dexametasone. Steroid drugs are commonly used for Pediatric treatment with no side effects when infrequently used and for short-time periods. The American Academy of Pediatrics rates it compatible with breastfeeding. WHO Model List of Essential Medicines (2002) rates it compatible with breastfeeding

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26750124
  2. http://rheumatology.oxfordjournals.org/content/early/2016/01/12/rheumatology.kev404.full.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/26129693
  4. http://www.ncbi.nlm.nih.gov/pubmed/25602023
  5. http://ecco-jcc.oxfordjournals.org/content/eccojc/9/2/107.full.pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/25200000
  7. http://onlinelibrary.wiley.com/doi/10.1111/apt.12949/epdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/24614280
  9. http://www.ncbi.nlm.nih.gov/pubmed/24261425
  10. http://www.ncbi.nlm.nih.gov/pubmed/23474350
  11. http://www.dldjournalonline.com/article/S1590-8658(13)00050-9/pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/22772888
  13. http://www.ncbi.nlm.nih.gov/pubmed/22379622
  14. http://www.ncbi.nlm.nih.gov/pubmed/22309336
  15. http://www.ncbi.nlm.nih.gov/pubmed/22018758
  16. http://www.ncbi.nlm.nih.gov/pubmed/22221203
  17. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04967.x/epdf
  18. http://www.ncbi.nlm.nih.gov/pubmed/22724311
  19. http://www.ncbi.nlm.nih.gov/pubmed/21371350
  20. http://www.ncbi.nlm.nih.gov/pubmed/21122553
  21. http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
  22. http://www.ncbi.nlm.nih.gov/pubmed/20671559
  23. http://www.ncbi.nlm.nih.gov/pubmed/21122490
  24. http://www.ncbi.nlm.nih.gov/pubmed/21172284
  25. http://download.journals.elsevierhealth.com/pdfs/journals/1873-9946/PIIS1873994609000269.pdf
  26. http://www.ncbi.nlm.nih.gov/pubmed/19170693
  27. http://www.ncbi.nlm.nih.gov/pubmed/18166549
  28. http://pediatrics.aappublications.org/content/121/1/e92.full.pdf
  29. http://www.ncbi.nlm.nih.gov/pubmed/17661756
  30. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2007.03397.x/epdf
  31. http://www.ncbi.nlm.nih.gov/pubmed/18239407
  32. http://www.ncbi.nlm.nih.gov/pubmed/17599074
  33. http://www.ncbi.nlm.nih.gov/pubmed/16409012
  34. http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_qr.pdf
  35. http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_full.pdf
  36. http://www.ncbi.nlm.nih.gov/pubmed/12829927
  37. http://www.ncbi.nlm.nih.gov/pubmed/11901392
  38. http://whqlibdoc.who.int/hq/2002/55732.pdf
  39. http://www.ncbi.nlm.nih.gov/pubmed/11336764
  40. http://www.ncbi.nlm.nih.gov/pubmed/11726078
  41. http://www.ncbi.nlm.nih.gov/pubmed/11757466
  42. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  43. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  44. http://www.ncbi.nlm.nih.gov/pubmed/10724046
  45. http://archinte.jamanetwork.com/data/Journals/INTEMED/11959/ira90005.pdf
  46. http://www.ncbi.nlm.nih.gov/pubmed/9458024
  47. http://www.ncbi.nlm.nih.gov/pubmed/9759153
  48. http://www.ncbi.nlm.nih.gov/pubmed/23282454
  49. http://www.ncbi.nlm.nih.gov/pubmed/7839055
  50. http://www.ncbi.nlm.nih.gov/pubmed/8453851
  51. http://www.ncbi.nlm.nih.gov/pubmed/8498418
  52. http://www.ncbi.nlm.nih.gov/pubmed/2316961
  53. http://www.ncbi.nlm.nih.gov/pubmed/2364575
  54. http://www.ncbi.nlm.nih.gov/pubmed/3690992
  55. http://www.ncbi.nlm.nih.gov/pubmed/3893608
  56. http://www.ncbi.nlm.nih.gov/pubmed/3998938
  57. http://www.ncbi.nlm.nih.gov/pubmed/6371564
  58. http://www.ncbi.nlm.nih.gov/pubmed/6874387
  59. http://www.ncbi.nlm.nih.gov/pubmed/6817481
  60. http://www.ncbi.nlm.nih.gov/pubmed/1211963
  61. http://www.ncbi.nlm.nih.gov/pubmed/1186783

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