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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Balsalazide during lactation?
Is it safe for a nursing mother and a child?

Prodrug of Mesalamine: medication compounded by Mesalazine and an inert transporter that is degraded by bacteria into Mesalazine (5-ASA) in the large intestine. It is badly absorbed by the intestine, serum levels are low with scant excretion into breast milk. No harm effects among breastfed infants from treated mothers have been reported, except for rare cases of diarrhea reported in the 80's with the use of Mesalazine compounds different to Balsalazide. In a review of 121 cases and 121 controls, the authors failed to observe those findings. (Moretti, 1989). Expert consensus supports the compatibility of Mesalazine and/or its prodrugs during breastfeeding.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/23749699
  2. http://medwiekurozwoj.pl/articles/2013-1-10.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/23749699
  4. http://www.ncbi.nlm.nih.gov/pubmed/22690068
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369996/pdf/WJG-18-2600.pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/21122553
  7. http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/21172284
  9. http://download.journals.elsevierhealth.com/pdfs/journals/1873-9946/PIIS1873994609000269.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/19633577
  11. http://www.ncbi.nlm.nih.gov/pubmed/19786762
  12. http://www.ncbi.nlm.nih.gov/pubmed/18239407
  13. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  14. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/15591526
  16. http://www.ncbi.nlm.nih.gov/pubmed/12833232
  17. http://www.latamjpharm.org/trabajos/22/3/LAJOP_22_3_4_1_S7X6Z4TSVV.pdf
  18. http://www.ncbi.nlm.nih.gov/pubmed/11726078
  19. http://www.ncbi.nlm.nih.gov/pubmed/9664201
  20. http://www.collectionscanada.gc.ca/obj/s4/f2/dsk1/tape11/PQDD_0010/MQ40845.pdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/23282454
  22. http://www.ncbi.nlm.nih.gov/pubmed/8009971
  23. http://www.ncbi.nlm.nih.gov/pubmed/8408729
  24. http://www.ncbi.nlm.nih.gov/pubmed/8102746
  25. http://www.ncbi.nlm.nih.gov/pubmed/8498418
  26. http://www.ncbi.nlm.nih.gov/pubmed/2309691
  27. http://www.ncbi.nlm.nih.gov/pubmed/2563532
  28. http://www.ncbi.nlm.nih.gov/pubmed/2702310
  29. http://www.ncbi.nlm.nih.gov/pubmed/2892343
  30. http://www.ncbi.nlm.nih.gov/pubmed/2864155

Comments  

+3 #3 Reviewer: 25-34 Male on Treatment for 1 to 6 months (Patient) 2019-05-18 03:55
Capsules are easy enough to swallow but the drugs was 100% not effective in treating my UC symptoms.
+3 #2 Reviewer: JustMeSDC, 55-64 Female on Treatment for 5 to less than 10 years (Patient) 2018-05-19 02:15
I have been on this medication for over 5 years. It has worked for me.
+3 #1 Reviewer: 35-44 Male on Treatment for 2 to less than 5 years (Patient) 2017-01-28 03:56
Has any one experienced lower leg pain - including cramps and/or tingling sometimes burning nerve pain?

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