1 1 1 1 1 1 1 1 1 1 Rating 4.90 (22 Votes)
Doctor

Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Fentanyl during lactation?
Is it safe for a nursing mother and a child?

Opium-derived analgesic that is used through several ways of administration (epidural, intravenous, mouth, skin). It is excreted into breast milk in non-significant amount without observed problems among infants from treated mothers. Plasma levels of those infants were undetectable. It has been authorized for treatment of small infants and neonates. After a mother has underwent anesthesia by the use of Fentanyl, she may breastfeed her baby as soon as her recovery and general conditions may permit it. Fentanyl stimulates secretion of Prolactin, however, after Lactation has been established, Prolactin level has a poor relationship with production of mother's milk. There is controversy about the effect of analgesic medication used for labor management (Epidural anesthesia with Fentanyl added or not ) on the initiation of breastfeeding, both on starting of phase II of Lactogenesis or the infant ability for suckling. Some studies have pointed out to a higher risk for a delay in the initiation of Lactogenesis II (milk coming in) for longer than 3 days after birth, even though it would not affect the weight loss of the newborn. Other studies have found a higher risk for a delay in the first latch-on at the breast, higher body temperature and irritability or somnolence. Some others however, failed to show the same findings. It appears to be of more paramount importance the women's support for the establishment and continuation of breastfeeding, than the negative effect that would be exerted by administration of analgesia or anesthesia during labor. Fentany has lesser effect than Pethidine (Demerol) on initiation of breastfeeding. It occurs a higher milk production and weight increase of the infant if there is an adequate pharmacological control of the pain that appears after vaginal birth or C-section. The American Academy of Pediatrics - says that is usually compatible with breastfeeding.

doctor

woomen

Would you like to ask something else about Fentanyl ?
Ask your question through the form below.

Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
  2. http://www.ncbi.nlm.nih.gov/pubmed/25558983
  3. http://www.ncbi.nlm.nih.gov/pubmed/24451212
  4. http://www.ncbi.nlm.nih.gov/pubmed/23523191
  5. http://www.midwiferyjournal.com/article/S0266-6138(13)00051-X/pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/25432659
  7. http://www.ijponline.net/content/pdf/s13052-014-0082-6.pdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/25492043
  9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297456/pdf/13052_2014_Article_99.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/23302971
  11. http://www.ncbi.nlm.nih.gov/pubmed/22579258
  12. http://www.giejournal.org/article/S0016-5107(12)00194-0/pdf
  13. http://www.ncbi.nlm.nih.gov/pubmed/22624720
  14. http://www.gastrojournal.org/article/S0016-5085(12)00681-6/pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/22166068
  16. http://www.ncbi.nlm.nih.gov/pubmed/21146977
  17. http://www.ncbi.nlm.nih.gov/pubmed/19912160
  18. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2009.06136.x/epdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/20627690
  20. http://www.ncbi.nlm.nih.gov/pubmed/19286842
  21. http://www.ncbi.nlm.nih.gov/pubmed/18454213
  22. http://www.ncbi.nlm.nih.gov/pubmed/17521903
  23. http://www.ncbi.nlm.nih.gov/pubmed/17134489
  24. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702531/pdf/1746-4358-1-24.pdf
  25. http://www.ncbi.nlm.nih.gov/pubmed/16765143
  26. http://www.ncbi.nlm.nih.gov/pubmed/17541461
  27. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1595306/pdf/JPE150050.pdf
  28. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  29. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  30. http://www.ncbi.nlm.nih.gov/pubmed/16306734
  31. http://www.ncbi.nlm.nih.gov/pubmed/15684016
  32. http://www.j-smu.com/pdf2/200501/200501114.pdf
  33. http://www.ncbi.nlm.nih.gov/pubmed/15957994
  34. http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2005.00548.x/epdf
  35. http://www.ncbi.nlm.nih.gov/pubmed/16113019
  36. http://www.ncbi.nlm.nih.gov/pubmed/16306720
  37. http://www.ncbi.nlm.nih.gov/pubmed/12774874
  38. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  39. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  40. http://www.ncbi.nlm.nih.gov/pubmed/8346780
  41. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.1993.tb07130.x/epdf
  42. http://www.ncbi.nlm.nih.gov/pubmed/1551153
  43. http://www.ncbi.nlm.nih.gov/pubmed/2350936
  44. http://www.ncbi.nlm.nih.gov/pubmed/2923932
  45. http://www.ncbi.nlm.nih.gov/pubmed/2963561

Comments  

+3 #2 Reviewer: Dona, 55-64 Female on Treatment for 6 months to less than 1 year (Patient) 2018-12-14 09:09
I think I have to use so much more of this than other opiods, Is there sugar in these lollipops?
+3 #1 Reviewer: mommom, 45-54 Female on Treatment for 10 years or more (Patient) 2018-03-21 08:17
This is great medicine, however, like most medcations, your body gets used to it, & the medicine is no longer as effective as it was in the beginining. It also taste terrible.

Add comment