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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Topiramate during lactation?
Is it safe for a nursing mother and a child?

Anticonvulsant used for treatment of epilepsy and migraine prophylaxis. It is moderately excreted into breast milk with the infant receiving just over 10% of the maternal weight-adjusted dose. Neither clinical nor psychomotor developmental effects have been observed in infants whose mothers were treated. Only a possibly related case of gastroenteritis that resolved after discontinuation of mother’s medication.Plasma levels of infants whose mothers were treated with topiramate have shown to be undetectable or pretty below (<1 mg / L) the recommended therapeutic level (5-20 mg / L). Check up the occurrence of diarrhea, irritability and lethargy in infants

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/27766590
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114206/pdf/40268_2016_Article_148.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/26330649
  4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539876/
  5. http://www.ncbi.nlm.nih.gov/pubmed/24908139
  6. http://www.seizure-journal.com/article/S1059-1311(14)00137-X/pdf
  7. http://www.ncbi.nlm.nih.gov/pubmed/25217187
  8. http://www.ncbi.nlm.nih.gov/pubmed/25667861
  9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307966/pdf/main.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/23985170
  11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844381/pdf/1824-7288-39-50.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/23178070
  13. http://www.ncbi.nlm.nih.gov/pubmed/22683887
  14. http://www.ncbi.nlm.nih.gov/pubmed/22770820
  15. http://www.seizure-journal.com/article/S1059-1311(12)00157-4/pdf
  16. http://www.ncbi.nlm.nih.gov/pubmed/19398680
  17. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475193/pdf/znl142.pdf
  18. http://www.ncbi.nlm.nih.gov/pubmed/19133709
  19. http://www.ncbi.nlm.nih.gov/pubmed/16932550
  20. http://www.nature.com/nrneurol/journal/v2/n4/pdf/ncpneuro0153.pdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/15857447
  22. http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2005.54804.x/epdf
  23. http://www.ncbi.nlm.nih.gov/pubmed/16302885
  24. http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2005.00323.x/epdf
  25. http://www.ncbi.nlm.nih.gov/pubmed/16404803
  26. http://www.ncbi.nlm.nih.gov/pubmed/15591613
  27. http://www.ncbi.nlm.nih.gov/pubmed/14504308
  28. http://www.ncbi.nlm.nih.gov/pubmed/12366729
  29. http://onlinelibrary.wiley.com/doi/10.1046/j.1528-1157.2002.12502.x/epdf
  30. http://www.ncbi.nlm.nih.gov/pubmed/10937463

Comments  

+3 #1 Reviewer: James, 45-54 on Treatment for 2 to less than 5 years (Patient) 2018-06-02 12:14
Chronic pain for 30 years and migraines a few times a week for many reasons. Migraine sufferers understand that anything is worth trying out. This has saved my life! Weight loss is a bonus!

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