Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Salmeterol during lactation? |
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Long-acting bronchodilator. At latest update no published data on excretion into breastmilk were found. Because of a high plasma protein-binding capacity and very low or undetectable plasma concentrations observed after inhalation (Cazzola 2002, AEMPS 2012) the excretion into breastmilk in significant amounts is unlikely. Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested. Experts and scientific societies consider the use of Salmeterol during breastfeeding as devoid of risk for the infant (Ellsworth 1994, McDonald 1996, Nelson 2001, National Asthma Education 2004). Terbutaline (see specific info), a molecule related to the same group of drugs, is excreted in non-significant amounts into breastmilk. |
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Would you like to ask something else about Salmeterol ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Synonyms
Trade Names
The main trade names in different countries containing in its composition Salmeterol:- Advair ™
- Aeromax ™
- Aerometrol Plus ™
- Aliflus ™
- Anasma ™
- Arial ™
- Atmadisc ™
- Aurituss ™
- Beglan ™
- Betamican ™
- Brexotide ™
- Brisair ™
- Brisomax ™
- Bromex (Chile) ™
- Byany ™
- Combitide ™
- Crivanil Plus ™
- Dilamax ™
- Esiflo ™
- Flixovent ™
- Flunacross-S ™
- Flutivent ™
- Fluxamol ™
- Forair ™
- Foxair ™
- Inaladuo ™
- Inaspir ™
- Lirtodac Plus ™
- Maizar ™
- Neumotide ™
- Plusvent ™
- Respiro ™
- Rolenium ™
- Salmeflo ™
- Salmetedur ™
- Salmeter ™
- Sereflo ™
- Seretaide ™
- Seretide ™
- Serevent ™
- Serobid ™
- Seroflo ™
- Tevacomb ™
- Thoreus ™
- Ultrabeta ™
- Veraspir ™
- Viani ™
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/20074099
- http://jtm.oxfordjournals.org/content/jtm/17/1/32.full.pdf
- http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_full.pdf
- http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_qr.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11825095
- http://www.ncbi.nlm.nih.gov/pubmed/11254828
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1746013/pdf/v056p00325.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/8937369
- http://www.ncbi.nlm.nih.gov/pubmed/7619245
- http://www.ncbi.nlm.nih.gov/pubmed/6586490
- http://www.ncbi.nlm.nih.gov/pubmed/7082541
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402083/pdf/brjclinpharm00195-0107.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/7082542
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402089/pdf/brjclinpharm00195-0109.pdf