Sulfamethoxazole & Trimethoprim

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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

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Is it allowed to take Sulfamethoxazole & Trimethoprim during lactation?
Is it safe for a nursing mother and a child?

Mixture of 5 parts of Sulfamethoxazole and 1 part of Trimethoprim. See info on items separately. Trimethoprim is excreted into breast milk at 4 to 10% of corrected pediatric dose. No adverse effects have been shown in breastfed infants. Used for treatment of infants older than one month. Sulfamethoxazole is excreted in low levels into breast milk.No adverse effects have been shown in breastfed infants. Cautious use for treatment of premature infants with hyperbilirubinemia or G-6-P-D deficiency is required. Avoid use in affected patients . Check-up for infant jaundice. Be aware of false negative results of bacterial cultures when the mother is on antibiotics and diarrheal disease due to intestinal flora imbalance. The American Academy of Pediatrics rates it compatible with breastfeeding. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding for older, healthy full- term infants. See below the information of these related products:

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Analogues

Synonyms

Trade Names

The main trade names in different countries containing in its composition Sulfamethoxazole & Trimethoprim:

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/24911394
  2. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/4-mastitis-protocol-english.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/24528912
  4. http://www.ncbi.nlm.nih.gov/pubmed/21894275
  5. http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/20074099
  7. http://jtm.oxfordjournals.org/content/jtm/17/1/32.full.pdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/19698015
  9. http://www.ncbi.nlm.nih.gov/pubmed/18819238
  10. http://www.aafp.org/afp/2008/0915/p727.pdf
  11. http://www.ncbi.nlm.nih.gov/pubmed/17343814
  12. http://www.ncbi.nlm.nih.gov/pubmed/16736949
  13. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  14. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  15. http://whqlibdoc.who.int/hq/2002/55732.pdf
  16. http://www.ncbi.nlm.nih.gov/pubmed/12431134
  17. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  18. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/11847854
  20. http://www.ncbi.nlm.nih.gov/pubmed/8498418
  21. http://www.ncbi.nlm.nih.gov/pubmed/1288560

Comments  

+3 #4 Reviewer: on Treatment for less than 1 month (Patient) 2019-05-07 07:30
Was prescribed this by an ER doc after a bee sting got infected. Certainly cleared the infection up quickly, but the side effects were horrible. Constipation, severe headache, swollen glands, and eventually a full-body rash and fever. Ended up going to my regular doc who had to give me a shot of cortizone to calm the inflamation. All symptoms disappeared within 1.5 days of stopping antibiotic.
+3 #3 Reviewer: 45-54 Female on Treatment for 2 to less than 5 years (Patient) 2018-02-07 09:36
I have been taking acne meds since I was 16 and nothing seemed to work. I am now 52 with adult acne and this is the ONLY med that seems to work. My doctor wants me to slowly decrease the usage and eventually get off of it. Seems to be working. I hope the bacteria stays away!! I loved this med.
+3 #2 Reviewer: Kay, 45-54 Female on Treatment for less than 1 month (Patient) 2017-06-19 10:11
Do not take this drug!! If you doctor prescribes this for a bacterial infection, immediately ask for something else. It can kill you! It almost killed me!!
+3 #1 Reviewer: Jay, 55-64 Female on Treatment for less than 1 month (Patient) 2017-05-26 09:12
People over 60 should not be prescribed this medicine with sulpha in it. I now know I am allergic to it and other 60 year olds probably are. I ached all over, still do 4 days after stopping. Vomiting, fever, diarrhea and still have a rash. Had to switch antibiotics to heal my bug bite.

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