Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Adalimumab during lactation? |
|
IgG1-monoclonal antibody directed against tumor necrosis factor used for treatment of auto-immune diseases like Rheumatoid Arthritis. Minimal or low excretion into breast milk due to high molecular weight. In breastfed babies whose mothers were on this medication plasma levels were undetectable and failed to show side effects. It should be avoid in the first two post-partum weeks since pass of significant amounts of IgG to the milk can occur in the first 3 - 4 post-partum days. |
|
Would you like to ask something else about Adalimumab ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Analogues
Trade Names
The main trade names in different countries containing in its composition Adalimumab:Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/26888948
- http://ard.bmj.com/content/early/2016/02/17/annrheumdis-2015-208840.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/26688268
- http://www.gastrojournal.org/article/S0016-5085(15)01773-4/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/26129693
- http://www.ncbi.nlm.nih.gov/pubmed/25819232
- http://onlinelibrary.wiley.com/doi/10.1111/ddg.12596/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/25829190
- http://www.reumatismo.org/index.php/reuma/article/download/reumatismo.2014.798/pdf_10
- http://www.ncbi.nlm.nih.gov/pubmed/25602023
- http://ecco-jcc.oxfordjournals.org/content/eccojc/9/2/107.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23897285
- http://www.ncbi.nlm.nih.gov/pubmed/24707132
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974516/pdf/WJG-20-3495.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/24964946
- https://s3-eu-west-1.amazonaws.com/thejournalhub/10.15570/actaapa.2014.7/actaapa.2014.7.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/25200000
- http://onlinelibrary.wiley.com/doi/10.1111/apt.12949/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/24614280
- http://www.ncbi.nlm.nih.gov/pubmed/24528912
- http://www.ncbi.nlm.nih.gov/pubmed/23200982
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913646/pdf/nihms-542223.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23102835
- http://www.ncbi.nlm.nih.gov/pubmed/23749699
- http://medwiekurozwoj.pl/articles/2013-1-10.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23474350
- http://www.dldjournalonline.com/article/S1590-8658(13)00050-9/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22690068
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369996/pdf/WJG-18-2600.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22221203
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04967.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/22858514
- http://www.ncbi.nlm.nih.gov/pubmed/22387837
- http://pdf.medrang.co.kr/Kjg/059/Kjg059-02-05.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22018758
- http://www.ncbi.nlm.nih.gov/pubmed/21122553
- http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/19885906
- http://www.ncbi.nlm.nih.gov/pubmed/20005982
- http://www.ncbi.nlm.nih.gov/pubmed/21063826
- http://www.ncbi.nlm.nih.gov/pubmed/21172284
- http://download.journals.elsevierhealth.com/pdfs/journals/1873-9946/PIIS1873994609000269.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/19505214
- http://www.ncbi.nlm.nih.gov/pubmed/19452290
- http://www.ncbi.nlm.nih.gov/pubmed/18504282
- http://rheumatology.oxfordjournals.org/content/47/suppl_3/iii28.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/18799245
- http://www.ncbi.nlm.nih.gov/pubmed/17334338
- http://www.ncbi.nlm.nih.gov/pubmed/16917239
- http://www.ncbi.nlm.nih.gov/pubmed/16831611
- http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/15888806