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Is it allowed to take Anakinra during lactation? |
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It is indicated for treatment of rheumatoid arthritis in combination with methrotexate (the latter is contraindicated during lactation). A 153-aminoacid containing polypeptide with a large molecular weight. Excretion into breast milk is unlikely and subsequent oral absorption would be nil especially after one week post partum. No adverse effect in breastfed infants has been reported. |
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Would you like to ask something else about Anakinra ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Trade Names
The main trade names in different countries containing in its composition Anakinra:Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/26888948
- http://ard.bmj.com/content/early/2016/02/17/annrheumdis-2015-208840.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/26750124
- http://rheumatology.oxfordjournals.org/content/early/2016/01/12/rheumatology.kev404.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/25819232
- http://onlinelibrary.wiley.com/doi/10.1111/ddg.12596/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/21985166
- http://www.ncbi.nlm.nih.gov/pubmed/19822718
- http://www.ncbi.nlm.nih.gov/pubmed/11520075
- http://www.ncbi.nlm.nih.gov/pubmed/8947960