The small dose and low absorption to the plasma in a majority of ophthalmic preparations that are topically used make a significant excretion into the milk unlikely. Minoxidil when taken by mouth is excreted into breast milk in a clinically non-significant amount without side-effects appearing among those infants whose mothers were on this medication. It is regarded as normal that the lose of hair occurs within the months after birth without relationship to breastfeeding but with the cease of resting phase of hair growth that occurs during pregnancy. Within 12 months after birth, that old hair is replace by new one without remaining baldness. The American Academy of Pediatrics states that it is usually compatible with breastfeeding.