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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Metformin during lactation?
Is it safe for a nursing mother and a child?

Oral antidiabetic medication used for treatment of Diabetes Type II, Obesity and Polycystic Ovarian Syndrome (PCOS). Biguanide drugs act by decreasing Neoglycogenesis (new formation of sugar) in the liver. Low risk of Hypoglycemia. Metformin is excreted into breast milk in non-significant amount and without harmful effect on breastfed infants of treated mothers, Obesity is associated with breastfeeding difficulties. In spite of Metformin has beneficial effect on Obesity, this is not true with PCOS because lactation capacity is related to growth of breast tissue during pregnancy which is not improved by the use of Metformin, Oral antidiabetic drugs are not effective for Diabetes Type I. For Diabetes Type II diet, physical exercise and breastfeeding may ameliorate glycemia levels. See remarks on mother's Diabetes Mellitus by consulting specific item.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Trade Names

The main trade names in different countries containing in its composition Metformin:

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/25073822
  2. http://www.elsevier.es/en-revista-medicina-clinica-english-edition--462-pdf-S2387020615000376-S300
  3. http://www.ncbi.nlm.nih.gov/pubmed/23178070
  4. http://www.ncbi.nlm.nih.gov/pubmed/22827167
  5. http://www.ncbi.nlm.nih.gov/pubmed/23185203
  6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506244/pdf/AMS-8-19715.pdf
  7. http://www.ncbi.nlm.nih.gov/pubmed/21575798
  8. http://www.ncbi.nlm.nih.gov/pubmed/21894275
  9. http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/20118196
  11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872944/pdf/zdd833.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/19366943
  13. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669004/pdf/0550371.pdf
  14. http://www.ncbi.nlm.nih.gov/pubmed/18277353
  15. http://www.ncbi.nlm.nih.gov/pubmed/18662299
  16. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561099/pdf/bcp0066-0564.pdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/17535842
  18. http://www.ncbi.nlm.nih.gov/pubmed/17367265
  19. http://www.ncbi.nlm.nih.gov/pubmed/16868063
  20. http://www.ncbi.nlm.nih.gov/pubmed/16737874
  21. http://www.ncbi.nlm.nih.gov/pubmed/16580387
  22. http://www.ncbi.nlm.nih.gov/pubmed/15932841
  23. http://www.ncbi.nlm.nih.gov/pubmed/15384618
  24. http://www.ncbi.nlm.nih.gov/pubmed/12545145
  25. http://www.nature.com/clpt/journal/v73/n1/pdf/clpt20039a.pdf
  26. http://www.ncbi.nlm.nih.gov/pubmed/12436333
  27. http://download.springer.com/static/pdf/785/art%253A10.1007%252Fs00125-002-0939-x.pdf?auth66=1398501700_1c7dffebb8a3efa18d55558678294755&ext=.pdf

Comments  

+3 #3 Reviewer: 65-74 Male on Treatment for 6 months to less than 1 year (Patient) 2019-02-12 11:41
Iam male67.after taking this medicine my fasting sugar level has come down to around 6mmol/L from 7/8.
+3 #2 Reviewer: 45-54 Female on Treatment for 6 months to less than 1 year (Patient) 2018-05-08 11:46
Although this medicine has gotten my sugars down and my A1c is 6.0,it has also caused weight gain and swelling . That is the part I am not happy with. The info that comes with the meds does warn about this but my doctor was not .
+3 #1 Reviewer: Blackfoot, 35-44 Male on Treatment for 1 to 6 months (Patient) 2017-11-24 05:57
The medicine is very good brought me down to 6 but I am not happy with the weight gain even with exercise and diet.

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