First-generation antihistamine, piperazine derived drug with mild sedative effect. It is metabolized into Cetirizine which is compatible with breastfeeding. (See info at specific item) At last update no relevant information concerning breastfeeding were found. Since it has been shown to be well tolerated by young infants for itching relief and because it is metabolized into Cetirizine, we would assume that there is a low risk for breastfeeding in short-term treatments. Follow-up for sedation or irritability in the infant and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.