Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Sevoflurane during lactation? |
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Volatile halogenated anesthetic administered by inhalation. Since the last update we have not found published data on its excretion in breast milk. 95% is excreted via the lung without having been metabolized.Several authors believe that the amount excreted in milk is minimal, therefore it is considered safe during breastfeeding (Dalal 2014, Hale 1999, Spigset 1994), as well as another anesthetic from the same family, halothane, which is considered compatible with breastfeeding by the American Academy of Pediatrics.The residual amount of fluoride that is produced is minimal and is chelated by the calcium in the milk. Given its rapid elimination from the body, it is possible to breastfeed as soon as the mother has recovered from the anesthesia. Breastfeeding before anesthesia reduces the need for sevoflurane and also propofol to maintain the anesthesia (Bhaskara 2016).General anesthesia in caesarean sections delays the start of breastfeeding with respect to epidural anesthesia (Kutlucan 2014).Professionals working in the operating rooms may inhale volatile anesthetics which may appear in milk from breastfeeding mothers (Cote 1976), but in clinically insignificant amounts, therefore breastfeeding is not contraindicated. |
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Would you like to ask something else about Sevoflurane ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Trade Names
The main trade names in different countries containing in its composition Sevoflurane:Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/27053781
- http://www.ncbi.nlm.nih.gov/pubmed/24372776
- http://www.ncbi.nlm.nih.gov/pubmed/25584032
- http://www.ncbi.nlm.nih.gov/pubmed/10578796
- http://www.ncbi.nlm.nih.gov/pubmed/8171959
- http://www.ncbi.nlm.nih.gov/pubmed/8346780
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.1993.tb07130.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/986147
- http://bja.oxfordjournals.org/content/48/6/541.full.pdf