Propofol

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Doctor

Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

woomen

Is it allowed to take Propofol during lactation?
Is it safe for a nursing mother and a child?

Because of a high protein-binding capacity and a high volume of distribution, excretion into the breast milk is non-significant. No side-effects were observed in breastfed infants of mothers who were administered this medication. The nursing mother may breastfeed the baby as soon as she is recovered from anesthesia. A transient increase in Prolactin plasma levels has been observed with Propofol anesthesia. A case of green-bluish discoloration of the milk has been reported after administration of Propofol plus other drugs. Authorized medication for use in infants older than 1 month.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Synonyms

Trade Names

The main trade names in different countries containing in its composition Propofol:

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
  2. http://www.ncbi.nlm.nih.gov/pubmed/22579258
  3. http://www.giejournal.org/article/S0016-5107(12)00194-0/pdf
  4. http://www.ncbi.nlm.nih.gov/pubmed/22624720
  5. http://www.gastrojournal.org/article/S0016-5085(12)00681-6/pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/20167123
  7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837001/pdf/1471-2253-10-1.pdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/19858894
  9. http://www.ncbi.nlm.nih.gov/pubmed/16765143
  10. http://www.ncbi.nlm.nih.gov/pubmed/17541461
  11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1595306/pdf/JPE150050.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  13. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  14. http://www.ncbi.nlm.nih.gov/pubmed/9852700
  15. http://www.ncbi.nlm.nih.gov/pubmed/8346780
  16. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.1993.tb07130.x/epdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/2152036
  18. http://www.ncbi.nlm.nih.gov/pubmed/2589672
  19. http://www.ncbi.nlm.nih.gov/pubmed/3498397

Comments  

+3 #3 Reviewer: 55-64 Female on Treatment for less than 1 month (Patient) 2019-05-11 02:04
First ever colonoscopy. No discomfort at all. Woke up alert. No grogginess. Only issue I had was dry Cotten mouth feeling, but that is minor in the scheme of things.
+3 #2 Reviewer: Don, 65-74 on Treatment for less than 1 month (Patient) 2018-12-03 03:05
Had my second endoscopy today where propofol was used. In previous procedures, including hip replacement, sedatives were used. The advantage for me is that when you wake up from the procedure, you are awake and aware. With the other forms of sedation I was groggy for hours after the procedure. I have experienced no adverse side effects from this medication, no nausea, etc. Both uses were in a hospital setting.
+3 #1 Reviewer: Propofol intravenous, 75 or over Male on Treatment for less than 1 month (Patient) 2017-02-06 12:23
Just had my second colonoscopy after my initial one 10 years ago. Propofol was administered by IV and was very effective, absolutely NO side effects. Much prefer it over conscious sedation like my first one.

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