Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Tranexamic Acid during lactation? |
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Anti-fibrinolytic drug that is used on the treatment and prophylaxis of hereditary angioedema, menorrhagia and other hemorrhagic disorders. It is excreted into breast milk in a non-significant amount: the concentration measured in the milk was 1% of plasma concentration (Verstraeten 1985, WHO 2010, Caballero 2012).Despite of that low observed concentration, an expert consensus did not recommend its use while breastfeeding (Caballero 2012). No clinical or developmental issues have been observed in the short and long term among 21 infants whose mothers were treated with it. (Gilad 2014). Scientific societies and some consensus of experts believe it is compatible the use of Tranexamic acid during breastfeeding (WHO 2010, Bouillet 2015). |
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Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Synonyms
Trade Names
The main trade names in different countries containing in its composition Tranexamic Acid:Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/25935791
- http://www.ncbi.nlm.nih.gov/pubmed/25025926
- http://www.ncbi.nlm.nih.gov/pubmed/22197274
- http://www.jacionline.org/article/S0091-6749(11)01830-6/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/20398351
- http://www.who.int/selection_medicines/committees/expert/18/applications/TRANEXAMIC_ACID_10_2.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/2580684
- http://www.ncbi.nlm.nih.gov/pubmed/7308275
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