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Is it allowed to take 6-Mercaptopurine during lactation? |
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Antineoplastic and iImmunosuppressive agent. Active metabolite of Azathioprine. Just tiny amounts of this drug have been detected in breast milk ( ). Several breastfed infants whose mothers were treated with it have failed to show side effects. |
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Would you like to ask something else about 6-Mercaptopurine ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/26888577
- http://www.ncbi.nlm.nih.gov/pubmed/26688268
- http://www.ncbi.nlm.nih.gov/pubmed/27760078
- http://www.zora.uzh.ch/id/eprint/134470/1/134470.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/25602023
- http://ecco-jcc.oxfordjournals.org/content/eccojc/9/2/107.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/25602023
- http://www.ncbi.nlm.nih.gov/pubmed/23897285
- http://www.ncbi.nlm.nih.gov/pubmed/24707132
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974516/pdf/WJG-20-3495.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23474350
- http://www.dldjournalonline.com/article/S1590-8658(13)00050-9/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23749699
- http://medwiekurozwoj.pl/articles/2013-1-10.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23675854
- http://onlinelibrary.wiley.com/doi/10.1111/apt.12334/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/22690068
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369996/pdf/WJG-18-2600.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22221203
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04967.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/22387837
- http://pdf.medrang.co.kr/Kjg/059/Kjg059-02-05.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21453877
- http://www.ncbi.nlm.nih.gov/pubmed/19885906
- http://www.ncbi.nlm.nih.gov/pubmed/21122553
- http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21122490
- http://www.ncbi.nlm.nih.gov/pubmed/28839543
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517153/pdf/flgastro-2009-000174.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/19566905
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2009.03996.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/18761704
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2008.03843.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/18239407
- http://www.ncbi.nlm.nih.gov/pubmed/17261122
- http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2006.01232.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/17661756
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2007.03397.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/16995866
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885151/pdf/bcp0062-0453.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/17132809
- http://www.ncbi.nlm.nih.gov/pubmed/16831611
- http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16712713
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526635/pdf/ar1957.pdf
- http://whqlibdoc.who.int/hq/2002/55732.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/6371564
- http://www.ncbi.nlm.nih.gov/pubmed/6817481