At date of last update were not found published data on its excretion into breast milk, Pharmacokinetic data (low protein-binding capacity) make likely excretion into breast milk in amounts that could be significant. Until more information on this drug is available, it is preferred other options that are known to be safer, especially during the neonatal period or in cases of prematurity. Because of a small dose and low absorption to the plasma in a majority of ophthalmic preparations that are topically used, a significant excretion into the milk is unlikely, thus it is considered of very low risk while breastfeeding in this cases. It would be advisable to press on the lacrimal area or tightly close the eyes for a couple of minutes (nasolacrimal occlusion) to minimize the systemic absorption.