It is excreted into breast milk in clinically non-significant amount. Not effects on the infant's physical and psychomotor development at both short or long-term were found. Variable levels of Prolactin secretion (increment or lowering), which were non-significant, were found after the use of Trazodone. Because there is less experience published than with other drugs of the same pharmacological group, it should be preferred the use of an alternative drug that is known to be safer in the neonatal period or prematurity.