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pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


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Is it allowed to take Carbon-13 labeled Urea during lactation?
Is it safe for a nursing mother and a child?

Carbon 13 is a natural, stable and non-radioactive isotope (Idifarm 2016, Osaka 2016) that is used to label urea for diagnostic purposes. Since the last update we have not found any published data on its excretion in breast milk. Urea is a natural component of the body and is also found in milk (Wheeler RA 1991, Ross SA 1985). The dose of urea from the breath test to rule out infection by helicobacter pylori is 100 mg, an inconsequential amount since the endogenous production of urea is 25-35 g daily (AEMPS 2004). Manufacturer's data indicate low risk for pregnancy and breastfeeding (Idifarm 2016, Isomed 2004).

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/1905752
  2. http://www.ncbi.nlm.nih.gov/pubmed/4093521

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