At date of last update were not found published data on its excretion into breast milk. Because of a small dose and low absorption to the plasma in a majority of ophthalmic preparations that are topically used, a significant excretion into the milk is unlikely, thus it is considered of very low risk while breastfeeding in this cases. It would be advisable to press on the lacrimal area or tightly close the eyes for a couple of minutes (nasolacrimal occlusion) to minimize the systemic absorption. The risk can be further minimized by the use of beta-blocking agents with a higher protein-binding capacity.