Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take CDP-870 during lactation? |
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Monoclonal antibody directed against TNF (tumoral necrosis factor) that is used for treatment of autoimmune diseases like Rheumatoid Arthritis and Crohn's Disease. Probably because of a high molecular weight, no detectable traces have been found in mother's milk. It is not absorbed by the gut which is even more protective for the nursing infant. No harm effect has been shown among breastfed infants whose mothers were treated with this medication. Avoid using it in the two post-partum weeks since significant excretion into the milk within the first 3 - 4 days after delivery and absorption by the infant is possible. |
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Would you like to ask something else about CDP-870 ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/26888948
- http://ard.bmj.com/content/early/2016/02/17/annrheumdis-2015-208840.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/26129693
- http://www.ncbi.nlm.nih.gov/pubmed/23897285
- http://www.ncbi.nlm.nih.gov/pubmed/23200982
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913646/pdf/nihms-542223.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23752881
- http://www.ncbi.nlm.nih.gov/pubmed/23474350
- http://www.dldjournalonline.com/article/S1590-8658(13)00050-9/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23749699
- http://medwiekurozwoj.pl/articles/2013-1-10.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22772888
- http://www.ncbi.nlm.nih.gov/pubmed/21157441
- http://www.ncbi.nlm.nih.gov/pubmed/19885906
- http://www.ncbi.nlm.nih.gov/pubmed/21122553
- http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21063826
- http://www.ncbi.nlm.nih.gov/pubmed/19452290
- http://www.ncbi.nlm.nih.gov/pubmed/18799245