Second-generation cephalosporin for oral and injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Voropaeva 1982, Amiraslanova 1985, Nakamura 1987). No adverse effects reported in breasted infants (Benyamini 2005). Intravenously administered Cefuroxime salt is not orally absorbed. Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.