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pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Clomipramine Hydrochloride during lactation?
Is it safe for a nursing mother and a child?

Excreted into breast milk in a clinically non-significant amount with no problems observed in breastfed infants from treated mothers. Levels found in the plasma of those infants were very low or undetectable. Because of a tiny excretion into the milk, symptoms due to deprivation syndrome would not be avoided by breastfeeding the infants whose mothers were taking this medication during pregnancy. Galactorrhea out of the breastfeeding period has been described.

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26204124
  2. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/18-use-of-antidepressants-protocol-english.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/24383525
  4. http://www.ncbi.nlm.nih.gov/pubmed/23979084
  5. http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/22283766
  7. http://www.ncbi.nlm.nih.gov/pubmed/21801198
  8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269588/pdf/bcp0073-0295.pdf
  9. http://www.ncbi.nlm.nih.gov/pubmed/20958101
  10. http://www.ncbi.nlm.nih.gov/pubmed/15169695
  11. http://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.161.6.1066
  12. http://www.ncbi.nlm.nih.gov/pubmed/15591613
  13. http://www.ncbi.nlm.nih.gov/pubmed/14645327
  14. http://www.jabfm.org/content/16/5/372.full.pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/14639936
  16. http://whqlibdoc.who.int/hq/2002/55732.pdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/10390297
  18. http://pediatrics.aappublications.org/content/104/1/e11.full.pdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/9186793
  20. http://www.ncbi.nlm.nih.gov/pubmed/9296322
  21. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042834/pdf/bcp_0652.pdf
  22. http://www.ncbi.nlm.nih.gov/pubmed/8780414
  23. http://www.ncbi.nlm.nih.gov/pubmed/7761234
  24. http://www.ncbi.nlm.nih.gov/pubmed/7836334
  25. http://www.ncbi.nlm.nih.gov/pubmed/7834964
  26. http://www.ncbi.nlm.nih.gov/pubmed/1894455
  27. http://www.ncbi.nlm.nih.gov/pubmed/1749054
  28. http://www.ncbi.nlm.nih.gov/pubmed/3602989
  29. http://www.ncbi.nlm.nih.gov/pubmed/4063616

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