Desvenlafaxine Succinate

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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

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Is it allowed to take Desvenlafaxine Succinate during lactation?
Is it safe for a nursing mother and a child?

It is a reuptake-inhibitor of Serotonin and Norepinephrine, and active metabolite of Venlafaxine. It is excreted in low amount into breast milk. The amount detected in the infant's plasma is in the range of 2% - 6% respective to the amount found in the mother's plasma that is considered to be much lower than that found when the mother takes Venlafaxine. Not relevant side-effects have been found in such infants.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26204124
  2. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/18-use-of-antidepressants-protocol-english.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/23178070
  4. http://www.ncbi.nlm.nih.gov/pubmed/20960017
  5. http://www.ncbi.nlm.nih.gov/pubmed/20958101
  6. http://www.ncbi.nlm.nih.gov/pubmed/20926994
  7. http://www.ncbi.nlm.nih.gov/pubmed/19661763
  8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902256/pdf/nihms139489.pdf
  9. http://www.ncbi.nlm.nih.gov/pubmed/19607765
  10. http://www.ncbi.nlm.nih.gov/pubmed/11849190
  11. http://www.ncbi.nlm.nih.gov/pubmed/9643618

Comments  

+3 #4 Reviewer: Willow, 55-64 Male on Treatment for 1 to 6 months (Patient) 2018-11-21 03:56
After a saliva test to see which drug works best, it turned out I needed to take desvenlafafaxine. Seemed to work, no special instructions.
+3 #3 Reviewer: 45-54 Female on Treatment for less than 1 month (Patient) 2018-04-28 09:51
I have celiac disease and was not aware till I called that the active ingredients contain gluten. Worst 3 weeks I have had in a long time.
+3 #2 Reviewer: 55-64 Female on Treatment for 1 to 6 months (Patient) 2017-10-06 07:30
I have been experiencing high levels of anger and irritability. I am so sad most of the time. I am taking 150 mg daily and wonder if it is too much. I never want to go anywhere or see people.
+3 #1 Reviewer: 25-34 Female on Treatment for less than 1 month (Patient) 2017-06-17 11:45
I have been on Pristiq for a week now. The first 2 nights were rough, I had bad anxiety and restlessness thoughout the night, I didnt sleep much but was wide awake for work the next morning and in GREAT spirts! My husband has noticed the changes and has said to me that it was nice to have the old me back. This pill has completely zapped my appetite though, and I have lost much weight in a week but its starting to come back but very slowly. The bad side effects seem to be tapering off slowly and they are my pupils dialating very large, and then mixing pristiq with caffine has given me restless legs syndrome only really noticable at night. Otherwise I am having a great experiance on this treatment. I have never tried an antidepressant before.

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