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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Hypericum perforatum during lactation?
Is it safe for a nursing mother and a child?

Herb commonly used from ancient times. Firm evidence is available on its effectiveness for treatment of depression, to the extent that it should be avoided a sudden stop of medication to prevent a rebound effect. It has been also topically used for the treatment of wounds, burns and eczema due to healing and antiseptical properties. Constituents are: Hypericin, Hyperforin and Quercetin. Antidepressant properties are attributed to Hypericin but mostly to Hyperforin. Quercetin is a flavonoid which is commonly found in many fruits and eatable vegetables. Hyperforin is excreted into breast milk in nil or clinically non-significant amount with not side-effects reported among breastfed infants from treated mothers, except for isolated and dubious cases of somnolence and colicky pain with spontaneous resolution with no medical intervention being required. Plasma levels in those infants were undetectable or close to the lower detectable point (0.1μg/L). Hypericin has not been detected in the breast milk. Quercetin levels found were as low as of few nanomols/L., and related to composition of fruits and vegetables of diet. It is most important to make sure that composition and amount of Hypericum contained in commercially available products is correct, do not take it without medical surveillance, avoid sudden stop and consider pharmacological interactions with many other medications.

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/25881578
  2. http://www.ncbi.nlm.nih.gov/pubmed/26204124
  3. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/18-use-of-antidepressants-protocol-english.pdf
  4. http://www.ncbi.nlm.nih.gov/pubmed/24535321
  5. http://www.ncbi.nlm.nih.gov/pubmed/23963751
  6. http://www.ncbi.nlm.nih.gov/pubmed/23979084
  7. http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
  8. http://www.ncbi.nlm.nih.gov/pubmed/23237648
  9. http://download.journals.elsevierhealth.com/pdfs/journals/0899-9007/PIIS089990071200319X.pdf
  10. https://thewomens.r.worldssl.net/images/uploads/fact-sheets/Herbal-traditional-medicines-in-breastfeeding.pdf
  11. http://www.ncbi.nlm.nih.gov/pubmed/22686865
  12. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523241/pdf/bfm.2011.0122.pdf
  13. http://www.ncbi.nlm.nih.gov/pubmed/20958101
  14. http://www.ncbi.nlm.nih.gov/pubmed/21894275
  15. http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
  16. http://www.ncbi.nlm.nih.gov/pubmed/21053786
  17. http://www.ncbi.nlm.nih.gov/pubmed/20155996
  18. http://www.ncbi.nlm.nih.gov/pubmed/18333769
  19. http://online.liebertpub.com/doi/pdfplus/10.1089/bfm.2007.9978
  20. http://www.ncbi.nlm.nih.gov/pubmed/18637192
  21. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483264/pdf/1472-6882-8-42.pdf
  22. http://www.ncbi.nlm.nih.gov/pubmed/17397549
  23. http://www.ncbi.nlm.nih.gov/pubmed/16566628
  24. http://www.ncbi.nlm.nih.gov/pubmed/17085775
  25. http://www.ncbi.nlm.nih.gov/pubmed/15702702
  26. http://www.ncbi.nlm.nih.gov/pubmed/12748451
  27. http://www.ncbi.nlm.nih.gov/pubmed/12927015
  28. http://www.ncbi.nlm.nih.gov/pubmed/11819157
  29. http://www.ncbi.nlm.nih.gov/pubmed/11486982
  30. http://apps.who.int/medicinedocs/pdf/s4927e/s4927e.pdf

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