Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Ibuprofen Arginine during lactation? |
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Nonsteroidal anti-inflammatory. Indicated in the treatment of fever, pains, rheumatoid arthritis and other rheumatic processes.Oral, intravenous and topical administration, every 6 to 8 hours. Their pharmacokinetic data (high percentage of protein binding, acidic character and short half-life) explain the insignificant or no milk passage observed (Rigourd 2014, Walter 1997, Townsend 1984, Albert 1984, Weibert 1982). No problems have been observed in infants whose mothers took it (Walter 1997, Ito 1993, Weibert 1982). Medication commonly used in Pediatrics. Authorized use after 6 months. The dose that an infant can receive through breast milk is hundreds of times lower than the therapeutic dose in the infant (Rigourd 2014, Walter 1997). American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).Eleventh WHO Model List of Essential Drugs: Compatible with breastfeeding (WHO / UNICEF 2002). Expert authors and medical associations consider it compatible with breastfeeding (Reece 2017, Bordini 2016, Noviani 2016, Davanzo 2014, Sachs 2013, Worthington 2013, Hutchinson 2013, Rowe 2013, Amir 2011, Chen 2010, Risser 2009, Østensen 2007, Spigset 2000 , Janssen 200, Nice 2000, Mitchell 1999, Goldsmith 1989, Needs 1985). It can be considered the analgesi |
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Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/27050859
- http://www.scielo.br/pdf/anp/v74n3/0004-282X-anp-74-03-0262.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/26888577
- http://www.ncbi.nlm.nih.gov/pubmed/25217187
- http://www.ncbi.nlm.nih.gov/pubmed/24695355
- http://www.ncbi.nlm.nih.gov/pubmed/23465038
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974500/pdf/nihms-566022.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23968886
- http://www.ncbi.nlm.nih.gov/pubmed/23979084
- http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23178070
- http://www.ncbi.nlm.nih.gov/pubmed/23968886
- http://www.ncbi.nlm.nih.gov/pubmed/21894275
- http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/20074099
- http://jtm.oxfordjournals.org/content/jtm/17/1/32.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/20000300
- http://www.aafp.org/afp/2009/1215/p1371.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/17599074
- http://whqlibdoc.who.int/hq/2002/55732.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11533352
- http://pediatrics.aappublications.org/content/108/3/776.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10937472
- http://www.ncbi.nlm.nih.gov/pubmed/11155610
- http://www.ncbi.nlm.nih.gov/pubmed/10724046
- http://archinte.jamanetwork.com/data/Journals/INTEMED/11959/ira90005.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10776186
- http://www.ncbi.nlm.nih.gov/pubmed/9278216
- http://www.ncbi.nlm.nih.gov/pubmed/8498418
- http://www.ncbi.nlm.nih.gov/pubmed/2657891
- http://www.ncbi.nlm.nih.gov/pubmed/3893608
- http://www.ncbi.nlm.nih.gov/pubmed/6720796
- http://www.ncbi.nlm.nih.gov/pubmed/6465162
- http://www.ncbi.nlm.nih.gov/pubmed/7184678