Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Indometacin during lactation? |
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It is excreted into breast milk in non-significant clinically amounts.There has not been side-effects described in children from treated mothers, except for a case reported in 1978 with convulsions in a newborn infant whose mother received a higher dose than recommended. However, a causal relationship was questioned by other author in the same publication. Usually, breast milk and infant plasma levels have been found to be undetectable. It has been successfully used with no side-effects on treated mothers who had high levels of Prostaglandin E (PGE) whose infants were suffering of “physiologic diarrhea) This drug is used in neonates.The American Academy of Pediatrics rates it as usually compatible with breastfeeding. |
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Would you like to ask something else about Indometacin ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/27050859
- http://www.scielo.br/pdf/anp/v74n3/0004-282X-anp-74-03-0262.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/20000300
- http://www.aafp.org/afp/2009/1215/p1371.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/17599074
- http://www.ncbi.nlm.nih.gov/pubmed/14599056
- http://www.ncbi.nlm.nih.gov/pubmed/14599073
- http://www.ncbi.nlm.nih.gov/pubmed/11533352
- http://pediatrics.aappublications.org/content/108/3/776.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10724046
- http://archinte.jamanetwork.com/data/Journals/INTEMED/11959/ira90005.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/7956501
- http://www.ncbi.nlm.nih.gov/pubmed/8346780
- http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.1993.tb07130.x/epdf
- http://www.ncbi.nlm.nih.gov/pubmed/12959288
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364613/pdf/brjclinpharm00027-0035.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/1768569
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368557/pdf/brjclinpharm00051-0083.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/7249487
- http://www.ncbi.nlm.nih.gov/pubmed/78421
- http://www.ncbi.nlm.nih.gov/pubmed/79940