Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Lincomycin Hydrochloride during lactation? |
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A Lincosamide type antibacterial drug which is structurally similar to clindamycin. As clindamycin, it is excreted in breast milk in clinically non-significant amount with no problems being reported in infants whose mothers were treated with it. Its low oral bioavailability that further decreases with simultaneous ingestion of food, hinders the drug passage to the infant plasma from ingested mother’s milk , except in preterm babies and immediate neonatal period, in which they may occur an increased intestinal permeability. Among infants whose mothers are treated with antibiotics, an alteration of the intestinal flora may appear. In case of infant's fever, the possibility of false negative results of bacterial cultures should be taken into account. |
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Would you like to ask something else about Lincomycin Hydrochloride ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/23141132
- http://www.ncbi.nlm.nih.gov/pubmed/21894275
- http://www.racgp.org.au/download/documents/AFP/2011/September/201109amir.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/7082533
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402074/pdf/brjclinpharm00195-0046.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/14274891