Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Magnesium-Aluminium Silicate during lactation? |
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A compound based on a hydrated Aluminum and Magnesium silicate mixture. Both substances contained in antacids do not concentrated into breast milk. Naturally occurring, the mean Magnesium concentration in the milk is 31 mg/L (range 15 – 64 mg/L) and not affected by the ingestion of Magnesium. After ingestion of antacids the Aluminum plasma levels increase from a basal-point of 7 μg/L to 55 μg/L at half-an-hour with a return to previous level 3 hours later. Although a minimal amount of Aluminum may be found in the milk, there are not shown side-effects in the infant. Mother's milk has a mean concentration of 49 μg/L of Aluminum which is much lower than the amount of 180-700 μg/L found in artificial formulas. Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability. Avoid chronic or excessive use. WHO Model List of Essential Medicines 2002: Aluminum hydroxide and Magnesium hydroxide are compatible with breastfeeding. |
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Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/21623498
- http://www.ncbi.nlm.nih.gov/pubmed/20807425
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939626/pdf/1471-2431-10-63.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16225482
- http://www.ncbi.nlm.nih.gov/pubmed/12868283
- http://www.ncbi.nlm.nih.gov/pubmed/10763902
- http://www.ncbi.nlm.nih.gov/pubmed/9804446
- http://www.ncbi.nlm.nih.gov/pubmed/10205441
- http://www.ncbi.nlm.nih.gov/pubmed/8031961
- http://www.ncbi.nlm.nih.gov/pubmed/2331424
- http://www.ncbi.nlm.nih.gov/pubmed/2864852
- http://www.ncbi.nlm.nih.gov/pubmed/6683754