Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Metrizoic Acid during lactation? |
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The X-ray contrast media with components like Metrizoic acid, Meglumine and Sodium have a content between 52 and 60% of Iodine. It has been withhold from the market.Metrizoate is excreted into breast milk in clinically non-significant amount (Nielsen, 1987: 0.3% of the maternal dose). The various iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk. Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk.Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant.The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination. Most radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait any time to resume nursing. |
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Would you like to ask something else about Metrizoic Acid ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.acr.org/quality-safety/resources/contrast-manual
- http://www.ncbi.nlm.nih.gov/pubmed/24838733
- http://cbseram.com/2014/08/18/uso-de-contrastes-radiologicos-en-la-mujer-lactante-y-en-ninos/
- https://cbseram.files.wordpress.com/2013/05/nc3bamero-1408-agosto-2014.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22403117
- http://pubs.rsna.org/doi/pdf/10.1148/rg.323115120
- http://www.ncbi.nlm.nih.gov/pubmed/22451541
- http://www.ajronline.org/doi/pdf/10.2214/AJR.11.7405
- http://www.ncbi.nlm.nih.gov/pubmed/18669732
- http://www.ncbi.nlm.nih.gov/pubmed/17872711
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952588/pdf/0530630.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/15609057
- http://www.ncbi.nlm.nih.gov/pubmed/11533352
- http://pediatrics.aappublications.org/content/108/3/776.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/2960342
- http://www.ncbi.nlm.nih.gov/pubmed/6220321
- http://www.ncbi.nlm.nih.gov/pubmed/7116094
- http://www.ncbi.nlm.nih.gov/pubmed/7237038
- http://www.ncbi.nlm.nih.gov/pubmed/13326552