Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Metronidazole Ovules during lactation? |
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Used for treatment of acne (Gel) and vaginitis (Gel, Ovules) Significant levels in breast milk are unlikely because of low content of Metronidazole in products for topical use (less than 1%) and low absorption by vaginal mucosa (Ovules: 25%, Gel: 56%). Through skin it is not absorbed at all. Like most medications for topical use, a poor absorption make it compatible with breastfeeding. Widely used for treatment of Giardia lamblia infections, even in small infants, without adverse effects reported. Metronidazole may produce a red discoloration of corporal fluids and bitter flavor of the milk with no harm effect on the child. |
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Would you like to ask something else about Metronidazole Ovules ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/23657872
- http://www.ncbi.nlm.nih.gov/pubmed/23914887
- http://www.ncbi.nlm.nih.gov/pubmed/23178070
- http://www.ncbi.nlm.nih.gov/pubmed/23749699
- http://medwiekurozwoj.pl/articles/2013-1-10.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21160459
- http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5912a1.htm
- http://www.ncbi.nlm.nih.gov/pubmed/21172284
- http://download.journals.elsevierhealth.com/pdfs/journals/1873-9946/PIIS1873994609000269.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/19585498
- http://www.ncbi.nlm.nih.gov/pubmed/17923223
- http://www.ncbi.nlm.nih.gov/pubmed/14583068
- http://www.ncbi.nlm.nih.gov/pubmed/14623482
- http://whqlibdoc.who.int/hq/2002/55732.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/12431134
- http://www.ncbi.nlm.nih.gov/pubmed/11847854
- http://www.ncbi.nlm.nih.gov/pubmed/10845129
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2144878/pdf/canfamphys00027-0067.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/9502459
- http://www.ncbi.nlm.nih.gov/pubmed/9596854
- http://www.ncbi.nlm.nih.gov/pubmed/9465933
- http://www.ncbi.nlm.nih.gov/pubmed/1288560
- http://www.ncbi.nlm.nih.gov/pubmed/3203060
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386498/pdf/brjclinpharm00097-0046.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/3099894
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1342181/pdf/bmjcred00263-0029.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/3865353
- http://www.ncbi.nlm.nih.gov/pubmed/6854509
- http://www.ncbi.nlm.nih.gov/pubmed/7200704
- http://www.ncbi.nlm.nih.gov/pubmed/6941457
- http://www.ncbi.nlm.nih.gov/pubmed/7454176
- http://www.ncbi.nlm.nih.gov/pubmed/6934434
- http://www.ncbi.nlm.nih.gov/pubmed/357408
- http://www.ncbi.nlm.nih.gov/pubmed/13901320
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1047447/pdf/brjvendis00126-0040.pdf