Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Nortriptyline during lactation? |
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It is an active metabolite of Amitriptyline. Excreted into breast milk in a clinically non-significant amount (Wisner 1997,Matheson 1988, Brixen1982) with no problems observed in breastfed infants from treated mothers (Wisner 2002, 1997 y 1991,Brixen1982). Levels found in the plasma of those infants were very low or undetectable Wisner 2006 y 1991). It is considered one of the safest antidepressants during lactation (Gentile 2014, Nielsen 2012, Hübner 2012, Pringsheim 2012, Davanzo 2011, Lanza 2009, ABM 2008, Weissman 2004). |
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Would you like to ask something else about Nortriptyline ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/26204124
- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/18-use-of-antidepressants-protocol-english.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/24383525
- http://www.ncbi.nlm.nih.gov/pubmed/23979084
- http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22787503
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394379/pdf/Dtsch_Arztebl_Int-109-0419.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22283766
- http://www.ncbi.nlm.nih.gov/pubmed/22683887
- http://www.ncbi.nlm.nih.gov/pubmed/20958101
- http://www.ncbi.nlm.nih.gov/pubmed/19661763
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902256/pdf/nihms139489.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/18333769
- http://online.liebertpub.com/doi/pdfplus/10.1089/bfm.2007.9978
- http://www.ncbi.nlm.nih.gov/pubmed/16855451
- http://www.ncbi.nlm.nih.gov/pubmed/15169695
- http://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.161.6.1066
- http://www.ncbi.nlm.nih.gov/pubmed/14645327
- http://www.jabfm.org/content/16/5/372.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/12124409
- http://www.ncbi.nlm.nih.gov/pubmed/10390297
- http://pediatrics.aappublications.org/content/104/1/e11.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/9441422
- http://www.ncbi.nlm.nih.gov/pubmed/9247422
- http://ajp.psychiatryonline.org/doi/pdf/10.1176/ajp.154.8.1174a
- http://www.ncbi.nlm.nih.gov/pubmed/9230638
- http://www.ncbi.nlm.nih.gov/pubmed/8780414
- http://www.ncbi.nlm.nih.gov/pubmed/8561220
- http://www.ncbi.nlm.nih.gov/pubmed/7726331
- http://www.ncbi.nlm.nih.gov/pubmed/7775366
- http://www.ncbi.nlm.nih.gov/pubmed/1894455
- http://www.ncbi.nlm.nih.gov/pubmed/1883004
- http://www.ncbi.nlm.nih.gov/pubmed/3191943
- http://www.ncbi.nlm.nih.gov/pubmed/6805016
- http://www.ncbi.nlm.nih.gov/pubmed/7366815
- http://www.ncbi.nlm.nih.gov/pubmed/495815
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