Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Olanzapine Embonate during lactation? |
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It is excreted in breast milk in clinically non-significant amount without problems observed in infants whose mothers were receiving this treatment, whether on psychomotor development, speech improvement and weight gaining.Drug plasma levels in these infants were undetectable or very low. In the neonatal period, isolated cases of sedation and / or withdrawal symptoms have been reported, possibly by accumulative mechanism during pregnancy or added effect from another drug. Some experts think that Olanzapine would be the one of choice during lactation among second-generation antipsychotic drugs (Uguz 2016). May induce increased plasma levels of Prolactin but less frequently and lower than other antipsychotic drugs. |
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Would you like to ask something else about Olanzapine Embonate ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/27028982
- http://www.ncbi.nlm.nih.gov/pubmed/25679127
- http://www.ncbi.nlm.nih.gov/pubmed/26539905
- http://www.ncbi.nlm.nih.gov/pubmed/26330649
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539876/
- http://www.ncbi.nlm.nih.gov/pubmed/25365434
- http://www.ncbi.nlm.nih.gov/pubmed/24938920
- http://www.ncbi.nlm.nih.gov/pubmed/23724438
- http://www.ncbi.nlm.nih.gov/pubmed/23902726
- http://www.ncbi.nlm.nih.gov/pubmed/23178070
- http://www.ncbi.nlm.nih.gov/pubmed/23979084
- http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21267028
- http://tidsskriftet.no/pdf/pdf2011/126-9.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/21034242
- http://www.ncbi.nlm.nih.gov/pubmed/21701632
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108712/pdf/dhps-2-205.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/18801835
- http://www.ncbi.nlm.nih.gov/pubmed/18370569
- http://www.ncbi.nlm.nih.gov/pubmed/18520614
- http://www.ncbi.nlm.nih.gov/pubmed/17291382
- http://www.ncbi.nlm.nih.gov/pubmed/14709955
- http://www.ncbi.nlm.nih.gov/pubmed/15591613
- http://www.ncbi.nlm.nih.gov/pubmed/12900304
- http://www.ncbi.nlm.nih.gov/pubmed/15152788
- http://www.ncbi.nlm.nih.gov/pubmed/12366877
- http://www.ncbi.nlm.nih.gov/pubmed/10761825
- http://www.ncbi.nlm.nih.gov/pubmed/10917399
- http://www.ncbi.nlm.nih.gov/pubmed/11048906
- http://www.ncbi.nlm.nih.gov/pubmed/9376336