Peginterferon alfa-2b

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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

woomen

Is it allowed to take Peginterferon alfa-2b during lactation?
Is it safe for a nursing mother and a child?

It is used in the treatment of leukemia, and, hepatitis B and C. Breast milk contains several interferon-like substances which contribute to its anti-viral action. High molecular weight of interferon accounts for its small secretion into breast milk. A minimal gastrointestinal absorption is commonly accepted. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26966579
  2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757692/pdf/MSI2016-6527458.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/25819232
  4. http://onlinelibrary.wiley.com/doi/10.1111/ddg.12596/epdf
  5. http://www.ncbi.nlm.nih.gov/pubmed/25207476
  6. http://www.ncbi.nlm.nih.gov/pubmed/24684929
  7. http://www.ncbi.nlm.nih.gov/pubmed/25415167
  8. http://www.ncbi.nlm.nih.gov/pubmed/22633835
  9. http://www.ncbi.nlm.nih.gov/pubmed/21988602
  10. http://www.ncbi.nlm.nih.gov/pubmed/20878174
  11. http://www.ncbi.nlm.nih.gov/pubmed/21330996
  12. http://www.ncbi.nlm.nih.gov/pubmed/21817183
  13. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  14. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/11216871
  16. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  17. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  18. http://www.ncbi.nlm.nih.gov/pubmed/11153157
  19. http://www.ncbi.nlm.nih.gov/pubmed/10887499
  20. http://www.ncbi.nlm.nih.gov/pubmed/8698119
  21. http://www.ncbi.nlm.nih.gov/pubmed/8896040
  22. http://www.ncbi.nlm.nih.gov/pubmed/7819084
  23. http://www.ncbi.nlm.nih.gov/pubmed/8457628
  24. http://www.ncbi.nlm.nih.gov/pubmed/1336606
  25. http://www.ncbi.nlm.nih.gov/pubmed/434888

Comments  

+3 #2 Reviewer: JennyLee, 25-34 Female on Treatment for 6 months to less than 1 year (Patient) 2018-09-15 11:15
I took this medication for 6months. I also took milk thistle and dandelion supplements. It has been almost 8 yrs later and my doctors say I am free of the virus.
+3 #1 Reviewer: onewiseguy, 45-54 Male on Treatment for 1 to 6 months (Patient) 2017-05-11 05:25
you have to stay postive about treatment before and doring and don,t be afade first dose will make you sick like haveing the flo for first 24 hours then IT gets easyer

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