Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Perprazole during lactation? |
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S-Enantiomer of Omeprazole with which shares similar characteristics. Due to a high serum-protein-binding capacity, Omeprazole is excreted into breast milk in non-significant amount without side-effects among breastfed infants from treated mothers. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Omeprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. Esomeprazole has been used for treatment of newborn and premature infants. Hyperprolactinemia and galactorrhea have been reported by the use of Omeprazole. |
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Would you like to ask something else about Perprazole ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.ncbi.nlm.nih.gov/pubmed/20726208
- http://www.ncbi.nlm.nih.gov/pubmed/19394048
- http://www.ncbi.nlm.nih.gov/pubmed/16893146
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781096/pdf/jCFP_v052_pg853.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16831611
- http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16225482
- http://www.ncbi.nlm.nih.gov/pubmed/11475467
- http://www.ncbi.nlm.nih.gov/pubmed/9582548
- http://www.ncbi.nlm.nih.gov/pubmed/2690330