It is composed by a complex mixture of phospholipids (phosphatidylcholine, phosphatidylserine, phosphatidylinositol) as a part of cell membranes and found in large amounts in the seed oil of several plants (soy, sunflower, and colza), egg yolk and liver. They are used in the food and pharmaceutical industry as softener and stabilizer. Also, as a medication for hyperlipidemia control. It has been also added to pumped breast milk to lessen loss of fat due to adherence to the surface of tubes used for enteral feeding. It is naturally found in the plasma, and, at higher levels in human milk. The mature milk contains more Coline than the colostrum or the mother milk of prematures. This content is also higher in breast milk than in industrial formulas. When used as a supplement, the concentration of Coline is moderately increased in the plasma, the milk and the serum of the infant. Supplementation with Coline does not enhance the cognitive capability of the infant. There is not scientific proof on the effectiveness for the treatment of mastitis, blocked ducts, nipple blisters or milk pearls.No adverse effects have been reported. Since a lack of toxicity at usual doses, it is believed to be safe while breastfeeding with a moderate use. See below the information of these related products: