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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Purinethiol during lactation?
Is it safe for a nursing mother and a child?

Antineoplastic and iImmunosuppressive agent. Active metabolite of Azathioprine. Just tiny amounts of this drug have been detected in breast milk ( ). Several breastfed infants whose mothers were treated with it have failed to show side effects.

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26888577
  2. http://www.ncbi.nlm.nih.gov/pubmed/26688268
  3. http://www.ncbi.nlm.nih.gov/pubmed/27760078
  4. http://www.zora.uzh.ch/id/eprint/134470/1/134470.pdf
  5. http://www.ncbi.nlm.nih.gov/pubmed/25602023
  6. http://ecco-jcc.oxfordjournals.org/content/eccojc/9/2/107.full.pdf
  7. http://www.ncbi.nlm.nih.gov/pubmed/25602023
  8. http://www.ncbi.nlm.nih.gov/pubmed/23897285
  9. http://www.ncbi.nlm.nih.gov/pubmed/24707132
  10. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974516/pdf/WJG-20-3495.pdf
  11. http://www.ncbi.nlm.nih.gov/pubmed/23474350
  12. http://www.dldjournalonline.com/article/S1590-8658(13)00050-9/pdf
  13. http://www.ncbi.nlm.nih.gov/pubmed/23749699
  14. http://medwiekurozwoj.pl/articles/2013-1-10.pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/23675854
  16. http://onlinelibrary.wiley.com/doi/10.1111/apt.12334/epdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/22690068
  18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369996/pdf/WJG-18-2600.pdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/22221203
  20. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04967.x/epdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/22387837
  22. http://pdf.medrang.co.kr/Kjg/059/Kjg059-02-05.pdf
  23. http://www.ncbi.nlm.nih.gov/pubmed/21453877
  24. http://www.ncbi.nlm.nih.gov/pubmed/19885906
  25. http://www.ncbi.nlm.nih.gov/pubmed/21122553
  26. http://ecco-jcc.oxfordjournals.org/content/eccojc/4/5/493.full.pdf
  27. http://www.ncbi.nlm.nih.gov/pubmed/21122490
  28. http://www.ncbi.nlm.nih.gov/pubmed/28839543
  29. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517153/pdf/flgastro-2009-000174.pdf
  30. http://www.ncbi.nlm.nih.gov/pubmed/19566905
  31. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2009.03996.x/epdf
  32. http://www.ncbi.nlm.nih.gov/pubmed/18761704
  33. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2008.03843.x/epdf
  34. http://www.ncbi.nlm.nih.gov/pubmed/18239407
  35. http://www.ncbi.nlm.nih.gov/pubmed/17261122
  36. http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2006.01232.x/epdf
  37. http://www.ncbi.nlm.nih.gov/pubmed/17661756
  38. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2007.03397.x/epdf
  39. http://www.ncbi.nlm.nih.gov/pubmed/16995866
  40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885151/pdf/bcp0062-0453.pdf
  41. http://www.ncbi.nlm.nih.gov/pubmed/17132809
  42. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  43. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  44. http://www.ncbi.nlm.nih.gov/pubmed/16712713
  45. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526635/pdf/ar1957.pdf
  46. http://whqlibdoc.who.int/hq/2002/55732.pdf
  47. http://www.ncbi.nlm.nih.gov/pubmed/6371564
  48. http://www.ncbi.nlm.nih.gov/pubmed/6817481

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