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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Venlafaxine Hydrochloride during lactation?
Is it safe for a nursing mother and a child?

It is a reuptake-inhibitor of Serotonin and Norepinephrine, and a precursor of Desvenlafaxine. Excreted into breast milk in amounts that may be clinically significant, which has been found in the plasma of breastfed infants from treated mothers. However, side-effects in those infants have not been shown. Various studies failed to show short or long-term side-effects among infants whose mothers were on Venlafaxine, both on physical or psychomotor development. It may induce galactorrhea. The poor extrauterine adaptation that may appear in neonates just after birth when the pregnant woman has been treated with selective reuptake-inhibitors of Serotonin like Venlafaxine or Mirtazapine, is seen to be mild if the baby is breastfed. In the case report of a mother who was taking this medication during pregnancy, her infant had shown amelioration of symptoms due to Abstinence Syndrome after having been breastfed. Women who use antidepressant medication during pregnancy are in need of more support for breastfeeding since they are at risk for early weaning.

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woomen

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Ask your question through the form below.

Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26204124
  2. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/18-use-of-antidepressants-protocol-english.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/25784291
  4. http://www.ncbi.nlm.nih.gov/pubmed/25217187
  5. http://www.ncbi.nlm.nih.gov/pubmed/24039427
  6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770341/pdf/ndt-9-1257.pdf
  7. http://www.ncbi.nlm.nih.gov/pubmed/23178070
  8. http://www.ncbi.nlm.nih.gov/pubmed/23979084
  9. http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/22787503
  11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394379/pdf/Dtsch_Arztebl_Int-109-0419.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/22283766
  13. http://www.ncbi.nlm.nih.gov/pubmed/22192462
  14. http://www.ncbi.nlm.nih.gov/pubmed/22299006
  15. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267169/pdf/CWHR-7-28.pdf
  16. http://www.ncbi.nlm.nih.gov/pubmed/20960017
  17. http://www.ncbi.nlm.nih.gov/pubmed/20807106
  18. http://www.ncbi.nlm.nih.gov/pubmed/19661763
  19. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902256/pdf/nihms139489.pdf
  20. http://www.ncbi.nlm.nih.gov/pubmed/19607765
  21. http://www.ncbi.nlm.nih.gov/pubmed/18978497
  22. http://www.ncbi.nlm.nih.gov/pubmed/19377024
  23. http://www.ncbi.nlm.nih.gov/pubmed/18794664
  24. http://www.ncbi.nlm.nih.gov/pubmed/18333769
  25. http://online.liebertpub.com/doi/pdfplus/10.1089/bfm.2007.9978
  26. http://www.ncbi.nlm.nih.gov/pubmed/17606668
  27. http://www.ncbi.nlm.nih.gov/pubmed/16776907
  28. http://www.ncbi.nlm.nih.gov/pubmed/15691224
  29. http://www.ncbi.nlm.nih.gov/pubmed/15367050
  30. http://www.ncbi.nlm.nih.gov/pubmed/15169695
  31. http://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.161.6.1066
  32. http://www.ncbi.nlm.nih.gov/pubmed/15591613
  33. http://www.ncbi.nlm.nih.gov/pubmed/12716242
  34. http://www.ncbi.nlm.nih.gov/pubmed/14645327
  35. http://www.jabfm.org/content/16/5/372.full.pdf
  36. http://www.ncbi.nlm.nih.gov/pubmed/11849190
  37. http://www.ncbi.nlm.nih.gov/pubmed/12124409
  38. http://www.ncbi.nlm.nih.gov/pubmed/11729040
  39. http://www.ncbi.nlm.nih.gov/pubmed/9643618

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