Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take YM-08316 during lactation? |
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Bronchodilator of long-lasting action. At latest update no published data on excretion into breast milk were found. Terbutaline which is a compound closely related to Formoterol is excreted into breast milk in non-significant amount.Salmeterol, another compound with similar characteristics, is also non-significantly excreted. With a relatively high molecular weight, excretion into breast milk seems unlikely. Expert consensus states that the use of inhaled bronchodilators is compatible with breastfeeding due to a minimal absorption and low levels achieved in the mother's plasma. Inhaled therapy with bronchodilators is preferred since they use a lower dose (less likelihood of excretion into milk) |
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Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_full.pdf
- http://www.nhlbi.nih.gov/health/prof/lung/asthma/astpreg/astpreg_qr.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11825095
- http://www.ncbi.nlm.nih.gov/pubmed/11254828
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1746013/pdf/v056p00325.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/8937369
- http://www.ncbi.nlm.nih.gov/pubmed/7619245
- http://www.ncbi.nlm.nih.gov/pubmed/6586490
- http://www.ncbi.nlm.nih.gov/pubmed/7082541
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402083/pdf/brjclinpharm00195-0107.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/7082542
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402089/pdf/brjclinpharm00195-0109.pdf