Peginterferon alfa

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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

woomen

Is it allowed to take Peginterferon alfa during lactation?
Is it safe for a nursing mother and a child?

It is used in the treatment of leukemia, and, hepatitis B and C. Breast milk contains several interferon-like substances which contribute to its anti-viral action. High molecular weight of interferon accounts for its small secretion into breast milk. A minimal gastrointestinal absorption is commonly accepted. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Synonyms

Trade Names

The main trade names in different countries containing in its composition Peginterferon alfa:

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/26966579
  2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757692/pdf/MSI2016-6527458.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/25819232
  4. http://onlinelibrary.wiley.com/doi/10.1111/ddg.12596/epdf
  5. http://www.ncbi.nlm.nih.gov/pubmed/25207476
  6. http://www.ncbi.nlm.nih.gov/pubmed/24684929
  7. http://www.ncbi.nlm.nih.gov/pubmed/25415167
  8. http://www.ncbi.nlm.nih.gov/pubmed/22633835
  9. http://www.ncbi.nlm.nih.gov/pubmed/21988602
  10. http://www.ncbi.nlm.nih.gov/pubmed/20878174
  11. http://www.ncbi.nlm.nih.gov/pubmed/21330996
  12. http://www.ncbi.nlm.nih.gov/pubmed/21817183
  13. http://www.ncbi.nlm.nih.gov/pubmed/16831611
  14. http://www.gastrojournal.org/article/S0016-5085(06)00865-1/pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/11216871
  16. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  17. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  18. http://www.ncbi.nlm.nih.gov/pubmed/11153157
  19. http://www.ncbi.nlm.nih.gov/pubmed/10887499
  20. http://www.ncbi.nlm.nih.gov/pubmed/8698119
  21. http://www.ncbi.nlm.nih.gov/pubmed/8896040
  22. http://www.ncbi.nlm.nih.gov/pubmed/7819084
  23. http://www.ncbi.nlm.nih.gov/pubmed/8457628
  24. http://www.ncbi.nlm.nih.gov/pubmed/1336606
  25. http://www.ncbi.nlm.nih.gov/pubmed/434888

Comments  

+3 #3 Reviewer: bubbles, 45-54 Female on Treatment for 1 to 6 months (Patient) 2019-05-05 05:54
i was very sore headaches allergy problems took 4 injection a week but since on pegasys and copegesys he stopped my allergie shots witch iv been very sick alot fever diareaha congestion head bad mood swings i work in factory whenits 80 its a 120in there having alot of trouble been on it for 1 month as of aug.17 2010
+3 #2 Reviewer: moteddybear, 45-54 Male on Treatment for 2 to less than 5 years (Patient) 2017-07-22 11:28
I started treatment in Feb of 2008, compleated it in Feb of 2009. off of it for 2 months and the Hep C came back at the same levels as before I started treatment! restarted treatment in May of 2009. and will go to the end of 2010. depressed, sick, tired and wondering if its worth all this, also major mood swings, My poor family!
+3 #1 Reviewer: angel465, 35-44 Female on Treatment for 1 to 6 months (Patient) 2017-04-02 10:35
I have had muscle aches, body pain, headaches,slight nauseau, and mild fever. Drinking lots of water and drinking 3 cups of coffee a day have helped me alot.

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