Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.
Is it allowed to take Morphine during lactation? |
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Excretion into breast milk is low (even lower when administered through Epidural Anesthesia). In addition, a low oral bioavailability makes that the amount present in the infant's plasma due to absorption from milk by the gut is low. Even though, level of drug has been found in the plasma of infants from treated mothers, harmful effects in the infants were not reported. Levels in the milk are lower and side-effects are fewer among infants whose mothers were treated with Morphine than with Pethidine. Some authorities consider Morphine as the elective opioid medication for breastfeeding mothers. Analgesia used during the birth process is related to a brief delayed of stage II of Lactogenesis (milk come-in). Morphine increases Prolactin level and may decrease Oxytocin level, but it would not be determinant for already established lactations. Avoidance of repetitive or chronic use and follow-up for somnolence and adequacy of infant nourishment is recommended. Bed-sharing should be avoid whenever this medication is used by parents. The American Academy of Pediatrics rates it as compatible with breastfeeding. |
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Would you like to ask something else about Morphine ? |
Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...
Analogues
Trade Names
The main trade names in different countries containing in its composition Morphine:- Actiskenan ™
- Algedol ™
- Amidiaz ™
- Analfin ™
- Analmorph ™
- Anamorph ™
- Astramorph ™
- Avinza ™
- Capros ™
- Compensan ™
- Contalgin ™
- DepoDur ™
- Depolan ™
- Dimorf ™
- Dolcontin (Finland, Norway, Sweden) ™
- Dolo Moff ™
- Doloral ™
- Dolq ™
- Doltard ™
- Duramor ™
- Duramorph ™
- Efemorf ™
- Embeda ™
- Filnarine ™
- GNO ™
- Graten ™
- Grumorph ™
- Infumorph ™
- Kadian ™
- Kapanol ™
- M-Dolor ™
- M-Eslon ™
- M-Stada ™
- M-beta ™
- M-long ™
- M-retard ™
- MOS ™
- MS Contin ™
- MS Contin (美施康定) ™
- MS Direct ™
- MS Mono ™
- MSI ™
- MSIR ™
- MSR ™
- MST ™
- MST Continus ™
- MXL ™
- Malfin ™
- Meifeikang (美菲康) ™
- Momex ™
- Mongol ™
- Morapid ™
- Morcontin ™
- Morf ™
- Morfenil ™
- Morficontin ™
- Morin ™
- Morphgesic ™
- Morphitroy ™
- Moscontin ™
- Mundidol ™
- Neocalmans ™
- Oramorph ™
- Ordine ™
- Painbreak ™
- RA Morph ™
- RMS ™
- Relimal ™
- Rhotard ™
- Roxanol ™
- SRM-Rhotard ™
- Sevre-Long ™
- Sevredol ™
- Shi Ni Kang (史尼康) ™
- Skenan ™
- Statex ™
- Stellorphine ™
- Substitol ™
- Twice ™
- Vendal ™
- Zomorph ™
Scientific literature
The level of risk for breastfeeding is confirmed in these scientific publications:- https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/24451212
- http://www.ncbi.nlm.nih.gov/pubmed/24451212
- http://www.ncbi.nlm.nih.gov/pubmed/23968886
- http://www.ncbi.nlm.nih.gov/pubmed/23979084
- http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23178070
- http://www.ncbi.nlm.nih.gov/pubmed/24565347
- http://www.unicef.org.uk/Documents/Baby_Friendly/Statements/UNICEF_UK_statement_bed_sharing_research_210513.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/23337847
- http://www.pap.es/files/1116-1449-pdf/pap53_10.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/22148986
- http://www.tandfonline.com/doi/pdf/10.3109/15563650.2011.635147?needAccess=true
- http://www.bfmed.org/Media/Files/Protocols/VERSION%20FINAL%20PROTOCOLO%206_Spanish.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/18333768
- http://www.bfmed.org/Media/Files/Protocols/Protocol_6.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/17872775
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949207/pdf/0531005.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/17541461
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1595306/pdf/JPE150050.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/16318956
- http://www.ncbi.nlm.nih.gov/pubmed/15167840
- http://www.ncbi.nlm.nih.gov/pubmed/14583068
- http://whqlibdoc.who.int/hq/2002/55732.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11772825
- http://www.ncbi.nlm.nih.gov/pubmed/11533352
- http://pediatrics.aappublications.org/content/108/3/776.full.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/10937472
- http://www.ncbi.nlm.nih.gov/pubmed/11013791
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2145042/pdf/canfamphys00031-0055.pdf
- http://www.ncbi.nlm.nih.gov/pubmed/11153344
- http://www.ncbi.nlm.nih.gov/pubmed/10937472
- http://www.ncbi.nlm.nih.gov/pubmed/10394089
- http://www.ncbi.nlm.nih.gov/pubmed/9296416
- http://www.ncbi.nlm.nih.gov/pubmed/7718105
- http://www.ncbi.nlm.nih.gov/pubmed/8260056
- http://www.ncbi.nlm.nih.gov/pubmed/8213024
- http://www.ncbi.nlm.nih.gov/pubmed/2231835
- http://www.ncbi.nlm.nih.gov/pubmed/2240676
- http://www.ncbi.nlm.nih.gov/pubmed/2800981
- http://www.ncbi.nlm.nih.gov/pubmed/6514937
- http://www.ncbi.nlm.nih.gov/pubmed/1176587
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