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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Morphine during lactation?
Is it safe for a nursing mother and a child?

Excretion into breast milk is low (even lower when administered through Epidural Anesthesia). In addition, a low oral bioavailability makes that the amount present in the infant's plasma due to absorption from milk by the gut is low. Even though, level of drug has been found in the plasma of infants from treated mothers, harmful effects in the infants were not reported. Levels in the milk are lower and side-effects are fewer among infants whose mothers were treated with Morphine than with Pethidine. Some authorities consider Morphine as the elective opioid medication for breastfeeding mothers. Analgesia used during the birth process is related to a brief delayed of stage II of Lactogenesis (milk come-in). Morphine increases Prolactin level and may decrease Oxytocin level, but it would not be determinant for already established lactations. Avoidance of repetitive or chronic use and follow-up for somnolence and adequacy of infant nourishment is recommended. Bed-sharing should be avoid whenever this medication is used by parents. The American Academy of Pediatrics rates it as compatible with breastfeeding.

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. https://abm.memberclicks.net/assets/DOCUMENTS/PROTOCOLS/15-analgesia-and-anesthesia-protocol-english.pdf
  2. http://www.ncbi.nlm.nih.gov/pubmed/24451212
  3. http://www.ncbi.nlm.nih.gov/pubmed/24451212
  4. http://www.ncbi.nlm.nih.gov/pubmed/23968886
  5. http://www.ncbi.nlm.nih.gov/pubmed/23979084
  6. http://pediatrics.aappublications.org/content/132/3/e796.full.pdf
  7. http://www.ncbi.nlm.nih.gov/pubmed/23178070
  8. http://www.ncbi.nlm.nih.gov/pubmed/24565347
  9. http://www.unicef.org.uk/Documents/Baby_Friendly/Statements/UNICEF_UK_statement_bed_sharing_research_210513.pdf
  10. http://www.ncbi.nlm.nih.gov/pubmed/23337847
  11. http://www.pap.es/files/1116-1449-pdf/pap53_10.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/22148986
  13. http://www.tandfonline.com/doi/pdf/10.3109/15563650.2011.635147?needAccess=true
  14. http://www.bfmed.org/Media/Files/Protocols/VERSION%20FINAL%20PROTOCOLO%206_Spanish.pdf
  15. http://www.ncbi.nlm.nih.gov/pubmed/18333768
  16. http://www.bfmed.org/Media/Files/Protocols/Protocol_6.pdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/17872775
  18. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949207/pdf/0531005.pdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/17541461
  20. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1595306/pdf/JPE150050.pdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/16318956
  22. http://www.ncbi.nlm.nih.gov/pubmed/15167840
  23. http://www.ncbi.nlm.nih.gov/pubmed/14583068
  24. http://whqlibdoc.who.int/hq/2002/55732.pdf
  25. http://www.ncbi.nlm.nih.gov/pubmed/11772825
  26. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  27. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  28. http://www.ncbi.nlm.nih.gov/pubmed/10937472
  29. http://www.ncbi.nlm.nih.gov/pubmed/11013791
  30. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2145042/pdf/canfamphys00031-0055.pdf
  31. http://www.ncbi.nlm.nih.gov/pubmed/11153344
  32. http://www.ncbi.nlm.nih.gov/pubmed/10937472
  33. http://www.ncbi.nlm.nih.gov/pubmed/10394089
  34. http://www.ncbi.nlm.nih.gov/pubmed/9296416
  35. http://www.ncbi.nlm.nih.gov/pubmed/7718105
  36. http://www.ncbi.nlm.nih.gov/pubmed/8260056
  37. http://www.ncbi.nlm.nih.gov/pubmed/8213024
  38. http://www.ncbi.nlm.nih.gov/pubmed/2231835
  39. http://www.ncbi.nlm.nih.gov/pubmed/2240676
  40. http://www.ncbi.nlm.nih.gov/pubmed/2800981
  41. http://www.ncbi.nlm.nih.gov/pubmed/6514937
  42. http://www.ncbi.nlm.nih.gov/pubmed/1176587

Comments  

+3 #2 Reviewer: Good saint, 65-74 Female on Treatment for less than 1 month (Patient) 2018-10-10 03:32
just chronic pain
+3 #1 Reviewer: 55-64 Female on Treatment for 10 years or more (Patient) 2017-08-09 05:59
After 2 back surgeries with resulting scar tissue attached to nerves and inability to do much of anything, and after hospitalization for severe uncontrollable pain, my physician put me on morphine. As he puts it, I am now functional. Although I have always been concerned about the "addiction" (my doctor hates it when I use that terminology), I am extremely grateful that I have a reasonably normal life and no longer spend most of my time in bed.

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