Is it allowed to take Vildagliptin during lactation? |
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It promotes pancreatic insulin secretion by inhibiting the DPP-4 enzyme that degrades the intestinal hormone GLP-1 that is activated upon eating (EMA 2016, Scheen 2011).Very low risk of hypoglycemia. Recommended dose: one to two doses daily. Since the last update we have not found published data on its excretion in breast milk. Its pharmacokinetic data (EMA 2016, Scheen 2011) - low molecular weight and low percentage of binding to plasma proteins - makes it likely that significant amounts will pass into breast milk. Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity. Diet, exercise, and breastfeeding improve blood sugar levels. See below the information of these related products: |
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Types of risk
VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...
LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...
HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...
VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...