Sirolimus in breastfeeding

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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.

Is it allowed to take Sirolimus during lactation? Is it safe for a nursing mother and a child?
On latest update relevant data on breastfeeding was not found. High molecular weight and plasma protein binding make excretion into breast milk unlikely. Low oral biodisponibility would be protective for breastfed children who are not newborn or premature. Some data indicates a risk for low milk production.
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VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

The main trade names in different countries containing in its composition Sirolimus:

The level of risk for breastfeeding is confirmed in these scientific publications:

+3 #1 Reviewer: knitz56, 45-54 Female on Treatment for 5 to less than 10 years (Patient) 2018-03-30 01:18

i have had a new kidney for 7 years, only a few health issues since, some from the meds but not serious.

Sirolimus