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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Sulpiride during lactation?
Is it safe for a nursing mother and a child?

Dopamine-selective antagonist that increases Prolactin serum levels which is used as anti-psychotic, anti-depressant, anti-emetic and prokinetic agent. Its property as galactogogue has been questioned because poor methodology used by published studies that intended to prove it. Doses at 50 mg twice-a-day after early post-partum for four weeks have been used to stimulate initiation of lactation without adverse effects in the mother. Excretion into breast milk is moderate, however, side-effects in breastfed infants from treated mothers were not observed. Best galactagogue effect is attained by promoting frequent breastfeeding on-demand along with the use of a proper lactation technique. Effective support to breastfeeding mothers, woman empowerment related to her ability to breastfeed and self-confidence are important factors to reinforce before start using galactagogue drugs.

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woomen

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Analogues

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/22220176
  2. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246777/pdf/OGI2012-562704.pdf
  3. http://www.ncbi.nlm.nih.gov/pubmed/21254794
  4. http://online.liebertpub.com/doi/pdfplus/10.1089/bfm.2010.0062
  5. http://www.bfmed.org/Media/Files/Protocols/Spanish%20Protocol%20Galactogogues%20and%20Appendix.pdf
  6. http://www.ncbi.nlm.nih.gov/pubmed/21332371
  7. http://online.liebertpub.com/doi/pdfplus/10.1089/bfm.2011.9998
  8. http://www.ncbi.nlm.nih.gov/pubmed/20816003
  9. http://ejournals.library.ualberta.ca/index.php/JPPS/article/download/6663/7429
  10. http://www.ncbi.nlm.nih.gov/pubmed/16809652
  11. http://www.jabfm.org/content/19/4/374.full.pdf
  12. http://www.ncbi.nlm.nih.gov/pubmed/16327907
  13. http://blues.sabinet.co.za/WebZ/Authorize?sessionid=0:autho=pubmed:password=pubmed2004&/AdvancedQuery?&format=F&next=images/ejour/m_samj/m_samj_v95_n9_a3.pdf
  14. http://www.ncbi.nlm.nih.gov/pubmed/12192964
  15. http://www.ncbi.nlm.nih.gov/pubmed/9254761
  16. http://www.ncbi.nlm.nih.gov/pubmed/8715241
  17. http://www.ncbi.nlm.nih.gov/pubmed/8764918
  18. http://www.ncbi.nlm.nih.gov/pubmed/1619566
  19. http://www.ncbi.nlm.nih.gov/pubmed/3620290
  20. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1387741/pdf/brjclinpharm00109-0014.pdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/3882143
  22. http://www.ncbi.nlm.nih.gov/pubmed/6361642
  23. http://www.ncbi.nlm.nih.gov/pubmed/6762263
  24. http://www.ncbi.nlm.nih.gov/pubmed/6807435
  25. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1499674/pdf/bmjcred00617-0013.pdf
  26. http://www.ncbi.nlm.nih.gov/pubmed/7102768
  27. http://www.ncbi.nlm.nih.gov/pubmed/6811008
  28. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1499572/pdf/bmjcred00624-0053a.pdf
  29. http://www.ncbi.nlm.nih.gov/pubmed/7418717
  30. http://www.ncbi.nlm.nih.gov/pubmed/429499
  31. http://www.ncbi.nlm.nih.gov/pubmed/1227717
  32. http://www.ncbi.nlm.nih.gov/pubmed/813995
  33. https://www.jstage.jst.go.jp/article/endocrj1954/22/5/22_5_457/_pdf

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